Facile synthesis of a phosphotriester intermediates for solution-phase preparation of oligonucleotide phosphorothioates

被引：0

作者：

Miyashita, T

Mori, K

Shinozuka, K

机构：

[1] Yamasa Corp, Div Biochem, Chiba 2880056, Japan

[2] Gunma Univ, Fac Engn, Dept Chem, Gunma 3760052, Japan

来源：

CHEMISTRY LETTERS | 1999年 / 01期

关键词：

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Fully protected 2'-deoxynucleoside phosphorothioate triester derivatives, which are key starting materials for the large-scale solution-phase preparation of phosphorothioate oligonucleotides, were easily synthesized by a new method starting from common, fully protected 2'-deoxynucleosides.

引用

页码：39 / 40

页数：2

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