Comparison of non-coplanar optimization of static beams and arc trajectories for intensity-modulated treatments of meningioma cases

被引:0
|
作者
Ventura, Tiago [1 ,2 ,3 ]
Rocha, Humberto [3 ,4 ,5 ]
Ferreira, Brigida da Costa [3 ,6 ,7 ]
Dias, Joana [3 ,4 ,5 ]
Lopes, Maria do Carmo [2 ,3 ,7 ]
机构
[1] Univ Aveiro, Phys Dept, Aveiro, Portugal
[2] Portuguese Oncol Inst Coimbra Francisco Gentil, EPE, Med Phys Dept, Coimbra, Portugal
[3] Inst Syst Engn & Comp Coimbra, Coimbra, Portugal
[4] Univ Coimbra, Econ Fac, Coimbra, Portugal
[5] Ctr Business & Econ Res, Coimbra, Portugal
[6] Univ Lisbon, Fac Ciencias, Inst Biofis & Engn Biomed, Lisbon, Portugal
[7] Univ Aveiro, I3N Phys Dept, Aveiro, Portugal
关键词
Beam angle optimization; Non-coplanar; Arc trajectory; VMAT; PARTIAL BREAST IRRADIATION; RADIATION-THERAPY; ANGLE OPTIMIZATION; ORIENTATION OPTIMIZATION; SINGLE-ARC; IMRT; COUCH; SELECTION; COPLANAR; ROTATION;
D O I
10.1007/s13246-021-01061-8
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Two methods for non-coplanar beam direction optimization, one for static beams and another for arc trajectories, were proposed for intracranial tumours. The results of the beam angle optimizations were compared with the beam directions used in the clinical plans. Ten meningioma cases already treated were selected for this retrospective planning study. Algorithms for non-coplanar beam angle optimization (BAO) and arc trajectory optimization (ATO) were used to generate the corresponding plans. A plan quality score, calculated by a graphical method for plan assessment and comparison, was used to guide the beam angle optimization process. For each patient, the clinical plans (CLIN), created with the static beam orientations used for treatment, and coplanar VMAT approximated plans (VMAT) were also generated. To make fair plan comparisons, all plan optimizations were performed in an automated multicriteria calculation engine and the dosimetric plan quality was assessed. BAO and ATO plans presented, on average, moderate global plan score improvements over VMAT and CLIN plans. Nevertheless, while BAO and CLIN plans assured a more efficient OARs sparing, the ATO and VMAT plans presented a higher coverage and conformity of the PTV. Globally, all plans presented high-quality dose distributions. No statistically significant quality differences were found, on average, between BAO, ATO and CLIN plans. However, automated plan solution optimizations (BAO or ATO) may improve plan generation efficiency and standardization. In some individual patients, plan quality improvements were achieved with ATO plans, demonstrating the possible benefits of this automated optimized delivery technique.
引用
收藏
页码:1273 / 1283
页数:11
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