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- [4] Mileage efficiency of carsCLEANER ENGINEERING AND TECHNOLOGY, 2021, 4Patankar, Neelesh A.Lin, JanePatankar, Tanvee N.
- [10] The road to better mileageTRIBOLOGY & LUBRICATION TECHNOLOGY, 2014, 70 (02) : 62 - 62Becker, Edward P.
Getting better mileage with logically primed CARs
被引：2
|作者：
Chen, Laurence C.
[1
]
Hou, Andrew J.
[1
]
Chen, Yvonne Y.
[1
,2
,3
]
机构：
[1] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA
[2] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA
[3] Univ Calif Los Angeles, Parker Inst Canc Immunotherapy Ctr, Los Angeles, CA 90095 USA
来源：
基金：
美国国家科学基金会;
关键词：
CELLS;
D O I：
10.1016/j.medj.2021.06.002
中图分类号：
R-3 [医学研究方法];
R3 [基础医学];
学科分类号：
1001 ;
摘要：
Although remarkably successful against liquid tumors, chimeric anti-gen receptor (CAR)-T cell therapy has been stymied by solid tumors, limited by inadequate specificity and poor efficacy. Pairing synthetic Notch (synNotch) receptors with CARs, Choe et al. and Hyrenius-Wittsten et al. engineer T cells that more precisely and potently combat solid tumors.
引用
收藏
页码：785 / 787
页数：3
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