Direct carboxamidation of indoles by palladium-catalyzed C-H activation and isocyanide insertion

被引：102
|
作者：
Peng, Jiangling [1 ,2 ]
Liu, Lanying [1 ,2 ]
Hu, Ziwei [1 ,2 ]
Huang, Jinbo [1 ,2 ]
Zhu, Qiang [1 ,2 ]
机构：
[1] Chinese Acad Sci, State Key Lab Resp Dis, Guangzhou Inst Biomed, 190 Kaiyuan Ave, Guangzhou 510530, Guangdong, Peoples R China
[2] Chinese Acad Sci, State Key Lab Resp Dis, Guangzhou Inst Hlth, Guangzhou 510530, Guangdong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 31期
基金：
美国国家科学基金会;
关键词：
FUNCTIONALIZATION; AMIDATION; MILD; 4-AMINOQUINAZOLINES; ALKENYLATION; HETEROARENES; ANNULATION; CYANATION; BONDS;
D O I：
10.1039/c2cc30351e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A selective C3 carboxamidation of indoles including free (N-H) ones by palladium-catalyzed sequential C-H activation-isocyanide insertion has been developed.
引用
收藏
页码：3772 / 3774
页数：3
相关论文
共 50 条
  • [21] Palladium-catalyzed C-H activation of amide derivatives
    Daugulis, Olafs
    Shabashov, Dmitry
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233
  • [22] Palladium-catalyzed intermolecular C-H amidation of indoles with sulfonyl azides
    Ziwei Hu
    Shuang Luo
    Qiang Zhu
    Science China Chemistry, 2015, 58 : 1349 - 1353
  • [23] Palladium-catalyzed intermolecular C-H amidation of indoles with sulfonyl azides
    Hu, Ziwei
    Luo, Shuang
    Zhu, Qiang
    SCIENCE CHINA-CHEMISTRY, 2015, 58 (08) : 1349 - 1353
  • [24] Palladium-catalyzed regioselective C-H alkynylation of indoles with bromoalkynes in water
    Wu, Wanqing
    Fang, Songjia
    Jiang, Guangbin
    Li, Meng
    Jiang, Huanfeng
    ORGANIC CHEMISTRY FRONTIERS, 2019, 6 (13) : 2200 - 2204
  • [25] Palladium-Catalyzed C-H Arylation of Indoles at the C7 Position
    Yang, Youqing
    Qiu, Xiaodong
    Zhao, Yue
    Mu, Yucheng
    Shi, Zhuangzhi
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 138 (02) : 495 - 498
  • [26] Palladium-catalyzed C-H arylation of indoles at the C7 position
    Science Foundation in China, 2016, (03) : 32 - 32
  • [27] Palladium-Catalyzed C-H Arylation of Indoles at the C7 Position
    Shi, Zhuangzhi (shiz@nju.edu.cn), 1600, American Chemical Society (138):
  • [28] Palladium-catalyzed β-selective C(sp2)-H carboxamidation of enamides by isocyanide insertion: synthesis of N-acyl enamine amides
    Xiong, Zhuang
    Liang, Dongdong
    Luo, Shuang
    ORGANIC CHEMISTRY FRONTIERS, 2017, 4 (06): : 1103 - 1106
  • [29] Palladium-Catalyzed Oxidative C-H/C-H Cross-Coupling of Indoles and Pyrroles with Heteroarenes
    Wang, Zhen
    Li, Kaizhi
    Zhao, Dongbing
    Lan, Jingbo
    You, Jingsong
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (23) : 5365 - 5369
  • [30] Recent advances in direct arylation via palladium-catalyzed aromatic C-H activation
    Li, Bi-Jie
    Yang, Shang-Dong
    Shi, Zhang-Jie
    SYNLETT, 2008, (07) : 949 - 957
12345