A new sesquiterpenoid glycoside from Saussurea involucrata

被引：10

作者：

Qi, Shizhou ^{[1
]}

Yang, Yiren ^{[1
]}

Xian, Xiaoyan ^{[1
]}

Li, Xianzhe ^{[1
]}

Gao, Huiyuan ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 07期

关键词：

antioxidant; anti-inflammatory; Saussurea involucrata; sesquiterpenoid glycoside; LACTONES; SEEDS; CONSTITUENTS;

D O I：

10.1080/14786419.2018.1543683

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Saussurea involucrata, known for the abundant bioactive components, is a precious traditional Chinese medicine. In this study, a novel guaiane sesquiterpenoid glycoside named (1R, 5R, 6R, 7R, 8S, 11S)-11, 13-dihydrodehydrocostuslactone-8-O-6'-2''(E)-butenoyl-beta-D-glucopyranoside (1), together with seven known compounds (2-8) were isolated from the dried aerial part of S. involucrata. Their structures were elucidated by spectroscopic and physico-chemical analyses. The antioxidant and anti-inflammatory activities of compound 1 were investigated. And compound 1 showed weak radical scavenging activity and low inhibitory activity on nitric oxide (NO) production.

引用

页码：943 / 949

页数：7

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