A new sesquiterpenoid glycoside from Saussurea involucrata

被引：10
|
作者：
Qi, Shizhou [1 ]
Yang, Yiren [1 ]
Xian, Xiaoyan [1 ]
Li, Xianzhe [1 ]
Gao, Huiyuan [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 07期
关键词：
antioxidant; anti-inflammatory; Saussurea involucrata; sesquiterpenoid glycoside; LACTONES; SEEDS; CONSTITUENTS;
D O I：
10.1080/14786419.2018.1543683
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Saussurea involucrata, known for the abundant bioactive components, is a precious traditional Chinese medicine. In this study, a novel guaiane sesquiterpenoid glycoside named (1R, 5R, 6R, 7R, 8S, 11S)-11, 13-dihydrodehydrocostuslactone-8-O-6'-2''(E)-butenoyl-beta-D-glucopyranoside (1), together with seven known compounds (2-8) were isolated from the dried aerial part of S. involucrata. Their structures were elucidated by spectroscopic and physico-chemical analyses. The antioxidant and anti-inflammatory activities of compound 1 were investigated. And compound 1 showed weak radical scavenging activity and low inhibitory activity on nitric oxide (NO) production.
引用
收藏
页码：943 / 949
页数：7
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