Synthesis of some novel 3-(2-chloro-3-quinolyl)-5-phenyl [1,3] thiazolo [2,3-c] [1,2,4] triazoles

被引：0

作者：

Dubey, PK ^{[1
]}

Rao, SS ^{[1
]}

Aparna, V ^{[1
]}

机构：

[1] JNT Univ, Coll Engn, Dept Chem, Hyderabad 500072, Andhra Pradesh, India

来源：

HETEROCYCLIC COMMUNICATIONS | 2003年 / 9卷 / 03期

关键词：

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various acetanilides (1) were treated with DMF and POCl3 complex (Vilsmeier's reagent) to obtain 2-chloro-3-quinolinecarboxaldehydes (2). The latter on condensation with thiosemi- carbazide in alcohol gave the corresponding thiosemicarbazones (3), which on treatment with substituted phenacyl bromides (4) in alchol gave quinoline substituted thiazoles (5). The dehydrogenative cyclisation of 5 was achieved with chloranil in refluxing toluene resulting in novel 3-(2-chloro-3-quinolyl)-6-phenyl [1,3] thiazolo [2,3-c] [1,2,4] triazoles (6) whose structures are supported by spectral data.

引用

页码：281 / 286

页数：6

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