Total leucoderma: A rare manifestation of cutaneous chronic graft-versus-host disease

被引:23
|
作者
Nagler, A
Goldenhersh, MA
LeviSchaffer, F
Bystryn, JC
Klaus, SN
机构
[1] HADASSAH UNIV HOSP,DEPT DERMATOL,IL-91120 JERUSALEM,ISRAEL
[2] HADASSAH UNIV HOSP,DEPT PHARMACOL,IL-91120 JERUSALEM,ISRAEL
[3] HEBREW UNIV JERUSALEM,IL-91120 JERUSALEM,ISRAEL
[4] KAPLAN COMPREHENS CANC CTR,NEW YORK,NY
关键词
D O I
10.1111/j.1365-2133.1996.tb06991.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
We describe a 14-year-old boy who developed total leucoderma during the course of chronic graft-versus-host disease, which developed after allogeneic bone marrow transplantation. Skin biopsy and dihydroxy-phenylalanine staining revealed a total absence of melanocytes from the epidermis. Cytotoxic anti-melanocyte antibodies were found in the patient's serum, and this probably explains the development of the leucoderma.
引用
收藏
页码:780 / 783
页数:4
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