Total leucoderma: A rare manifestation of cutaneous chronic graft-versus-host disease

被引：23
|
作者：
Nagler, A
Goldenhersh, MA
LeviSchaffer, F
Bystryn, JC
Klaus, SN
机构：
[1] HADASSAH UNIV HOSP,DEPT DERMATOL,IL-91120 JERUSALEM,ISRAEL
[2] HADASSAH UNIV HOSP,DEPT PHARMACOL,IL-91120 JERUSALEM,ISRAEL
[3] HEBREW UNIV JERUSALEM,IL-91120 JERUSALEM,ISRAEL
[4] KAPLAN COMPREHENS CANC CTR,NEW YORK,NY
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1996年 / 134卷 / 04期
关键词：
D O I：
10.1111/j.1365-2133.1996.tb06991.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
We describe a 14-year-old boy who developed total leucoderma during the course of chronic graft-versus-host disease, which developed after allogeneic bone marrow transplantation. Skin biopsy and dihydroxy-phenylalanine staining revealed a total absence of melanocytes from the epidermis. Cytotoxic anti-melanocyte antibodies were found in the patient's serum, and this probably explains the development of the leucoderma.
引用
收藏
页码：780 / 783
页数：4
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