A new bioactive ursane-type triterpenoid from Croton bonplandianum Bail

被引：13
|
作者：
Ghosh, Pranab [1 ]
Mandal, Amitava [1 ]
Rasul, Mohammad Golam [1 ]
机构：
[1] Univ N Bengal, Dept Chem, Darjeeling 734013, India
来源：
JOURNAL OF CHEMICAL SCIENCES | 2013年 / 125卷 / 02期
关键词：
Croton bonplandianum; 3 alpha-hydroxy-urs-12,15-dien; antifungal; ACID;
D O I：
10.1007/s12039-013-0387-9
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new triterpenoid 3 alpha-hydroxy-urs-12,15-dien (1) of ursane skeleton along with three others, viz. oleanolic acid (2) and ursolic acid (3) and beta-sitosterol (4) were isolated from the root of Croton bonplandianum Bail. Their chemical structures were established on the basis of spectroscopic analysis (IR, 1D NMR, 2D NMR, Mass, etc.) and by chemical means. A probable biosynthetic pathway of compound 1 was also proposed. Preliminary investigation with the new compound showed potent activity against a series of fungal pathogens.
引用
收藏
页码：359 / 364
页数：6
相关论文
共 50 条
  • [21] Ursane-Type Saponins from Zygophyllum cornutum
    Bencharif-Betina, Soumeya
    Miyamoto, Tomofumi
    Tanaka, Chiaki
    Kabouche, Zahia
    Mitaine-Offer, Anne-Claire
    Lacaille-Dubois, Marie-Aleth
    NATURAL PRODUCT COMMUNICATIONS, 2013, 8 (05) : 573 - 574
  • [22] Three new ursane-type triterpenes from the leaves of Rehmannia glutinosa
    Zhang, Yan-Li
    Feng, Wei-Sheng
    Zheng, Xiao-Ke
    Cao, Yan-Gang
    Lv, Yan-Yan
    Chen, Hui
    Kuang, Hai-Xue
    FITOTERAPIA, 2013, 89 : 15 - 19
  • [23] New ursane-type triterpenes from the root bark of Calotropis procera
    Ibrahim, Sabrin R. M.
    Mohamed, Gamal A.
    Shaala, Lamiaa A.
    Banuls, Laetitia Moreno Y.
    Van Goietsenoven, Gwendoline
    Kiss, Robert
    Youssef, Diaa T. A.
    PHYTOCHEMISTRY LETTERS, 2012, 5 (03) : 490 - 495
  • [24] A new ursane-type triterpene, cymosic acid from Rosa cymosa
    Wu, Xiao-Peng
    Zhang, Xiao-Po
    Ma, Guo-Xu
    Han, Mo
    Xu, Mu-Die
    Wu, Hai-Feng
    Huang, Xiao-Yan
    Huang, Zhen
    Yang, Jun-Shan
    Yuan, Jing-Quan
    Xu, Xu-Dong
    Zhong, Xiao-Ming
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2014, 16 (04) : 422 - 425
  • [25] Kalaic acid, a new ursane-type saponin from Musanga cecropioides
    Lontsi, D
    Sondengam, BL
    Bodo, B
    Martin, MT
    PLANTA MEDICA, 1998, 64 (02) : 189 - 191
  • [26] A New Ursane-Type Triterpene from the Roots of Salvia miltiorrhiza Bunge
    Le Quoc Hung
    Phuong Thien Thuong
    Nguyen Huu Tung
    RECORDS OF NATURAL PRODUCTS, 2019, 13 (05) : 429 - 433
  • [27] Three New Ursane-Type Triterpenoids from the Stems of Saprosma merrillii
    Zhang, Dashuai
    Chen, Wenhao
    Chen, Wenxing
    Song, Xiaoping
    Han, Changri
    Wang, Yan
    Chen, Guangying
    MOLECULES, 2013, 18 (12) : 14496 - 14504
  • [28] Lupane and Ursane-Type Triterpenoids from Pergularia tomentosa
    Halima S. Al Hinai
    Wafaa M. Al-Subhi
    Fatma Rashid S. Al-Rubaiai
    Syed I. Hassan
    Neelam Sherwani
    Majekodunmi O. Fatope
    Chemistry of Natural Compounds, 2018, 54 : 790 - 792
  • [29] LUPANE AND URSANE-TYPE TRITERPENOIDS FROM Pergularia tomentosa
    Al Hinai, Halima S.
    Al-Subhi, Wafaa M.
    Al-Rubaiai, Fatma Rashid S.
    Hassan, Syed, I
    Sherwani, Neelam
    Fatope, Majekodunmi O.
    CHEMISTRY OF NATURAL COMPOUNDS, 2018, 54 (04) : 790 - 792
  • [30] New ursane-type triterpenic esters from the stem bark of Thevetia peruviana
    Ali, M
    Ravinder, E
    Ramachandram, R
    PHARMAZIE, 2000, 55 (05): : 385 - 389
12345