Facile One-Pot Synthesis of N-acyl-1H-1,2,3-benzotriazoles from Internal and Terminal Olefinic Fatty Acids and Their Antimicrobial Screening

被引：6
|
作者：
Rauf, Abdul [1 ]
Gangal, Saloni [1 ]
机构：
[1] Aligarh Muslim Univ, Dept Chem, Aligarh 202002, Uttar Pradesh, India
来源：
JOURNAL OF OLEO SCIENCE | 2008年 / 57卷 / 08期
关键词：
Fatty acids; N-acyl-1H-1,2,3-benzotriazoles; benzotriazole; thionyl chloride; antifungal activity;
D O I：
10.5650/jos.57.453
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
N-acyl-1H-1,2,3-benzotriazoles were prepared in good yields by the reaction of benzotriazole and thionyl chloride with olefinic fatty acids under mild reaction conditions. The new compounds 1-(undec-10-enoyl)-1H-1,2,3-benzotriazole (5a),1-[(Z)-octadec-9-enoyl]-1H-1,2,3-benzotriazole (5b), 1-[(9Z,12R)-12-hydroxyoctadec-9-enoyl]-1H-1,2,3-benzotriazole (5c), 1-[(9R,12Z)-9-hydroxyoctadec-12-enoyl]-1H-1,2,3-benzotriazole (5d) formed were characterized on the basis of elemental analysis and spectral data. All the newly synthesized compounds (5a-5d) were screened for their antimicrobial activity and showed good antifungal activity.
引用
收藏
页码：453 / 457
页数：5
相关论文
共 50 条
  • [31] A facile and convenient approach for the one-pot synthesis of 2,4(1H,3H)-quinazolinediones
    Mahnaz Sharafi-Kolkeshvandi
    Farzad Nikpour
    Chinese Chemical Letters, 2012, 23 (04) : 431 - 433
  • [32] One-pot multicomponent click synthesis of some novel 1,4-disubstituted-1H-1,2,3-triazoles from alkenes
    Keshavarz, Mosadegh
    IRANIAN CHEMICAL COMMUNICATION, 2018, 6 (02) : 134 - 142
  • [33] One-pot synthesis of 2,4,5-trisubstituted oxazoles from N-acyl amino acids by a combination of cyclodehydration with N,N′-diisopropylcarbodiimide and Wittig olefination
    Huang, Wenhua
    Dong, Guangping
    Mijiti, Zumureti
    TETRAHEDRON, 2012, 68 (04) : 977 - 981
  • [34] Facile One-Pot Synthesis of Monosubstituted 1-Aryl-1H-1,2,3-triazoles from Arylboronic Acids and Prop-2-ynoic Acid (=Propiolic Acid) or Calcium Acetylide (=Calcium Carbide) as Acetylene Source
    Yang, Qing
    Jiang, Yubo
    Kuang, Chunxiang
    HELVETICA CHIMICA ACTA, 2012, 95 (03) : 448 - 454
  • [35] One-Pot Enzyme Cascade for Controlled Synthesis of Furancarboxylic Acids from 5-Hydroxymethylfurfural by H2O2 Internal Recycling
    Jia, Hao-Yu
    Zong, Min-Hua
    Zheng, Gao-Wei
    Li, Ning
    CHEMSUSCHEM, 2019, 12 (21) : 4764 - 4768
  • [36] One-pot synthesis of quinazolin-4(3 H)-ones and 2,3-dihydroquinazolin-4(1 H)-ones utilizing N-(2-aminobenzoyl)benzotriazoles
    Senol, Ilbilge Merve
    Celik, Ilhami
    Avan, Ilker
    TURKISH JOURNAL OF CHEMISTRY, 2019, 43 (06) : 1580 - +
  • [37] A facile and one pot synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from terminal alkynes and phenacyl azides prepared from styrenes by CAN oxidant and sodium azide
    Mosadegh Keshavarz
    Rashid Badri
    Molecular Diversity, 2011, 15
  • [38] A facile and one pot synthesis of 1,4-disubstituted-1H-1,2,3-triazoles from terminal alkynes and phenacyl azides prepared from styrenes by CAN oxidant and sodium azide
    Keshavarz, Mosadegh
    Badri, Rashid
    MOLECULAR DIVERSITY, 2011, 15 (04) : 957 - 962
  • [39] A One-pot Facile Construction of 1H-1,2,3-Triazolyl 1,2-Dihydropyridyl Derivatives and Evaluation of Bioactivity Profile
    Rajkumar, Kommera
    Murthy, Thampunuri Ramalinga
    Zehra, Amtul
    Khursade, Parag Sakharam
    Kaliyendi, Shasi Vardhan
    Tiwari, Ashok Kumar
    Prakasham, Reddy Shetty
    Raju, Bhimapaka China
    CHEMISTRYSELECT, 2018, 3 (48): : 13729 - 13735
  • [40] The one-pot synthesis of 4-aryl-1H-1,2,3-triazoles without azides and metal catalization
    He, Yun
    Sun, Erxiao
    Zhao, Yi
    Hai, Li
    Wu, Yong
    TETRAHEDRON LETTERS, 2014, 55 (01) : 111 - 115
12345