Model mis-specification and overestimation of the intraclass correlation coefficient in cluster randomized trials

被引：12
|
作者：
Giraudeau, B
机构：
[1] Fac Med Tours, INSERM, CIC 202, F-37032 Tours, France
[2] Univ Paris 07, INSERM, Biostat & Epidemiol Clin, U 717, Paris, France
来源：
STATISTICS IN MEDICINE | 2006年 / 25卷 / 06期
关键词：
bias; cluster randomized trial; intraclass correlation coefficient; mixed-effects model; one-way random effects model;
D O I：
10.1002/sim.2260
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Intraclass correlation coefficient (ICC) estimates must be provided when reporting the results of a cluster randomized trial. This study demonstrates that estimating this parameter with one-way ANOVA and an underlying mixed-effects statistical model leads to biased estimates. The bias depends on the effect size of the studied treatment. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：957 / 964
页数：8
相关论文
共 50 条
12345