Dual-mode laparoscopic fluorescence image-guided surgery using a single camera

被引：21
|
作者：
Gray, Daniel C. [1 ]
Kim, Evgenia M. [1 ]
Cotero, Victoria E. [1 ]
Bajaj, Anshika [1 ]
Staudinger, V. Paul [1 ]
Hehir, Cristina A. Tan [1 ]
Yazdanfar, Siavash [1 ]
机构：
[1] GE Global Res, Niskayuna, NY 12309 USA
来源：
BIOMEDICAL OPTICS EXPRESS | 2012年 / 3卷 / 08期
关键词：
NEAR-INFRARED FLUORESCENCE; INTRAOPERATIVE ELECTRICAL-STIMULATION; IN-VIVO; PROSTATE-CANCER; CARDIAC-SURGERY; RISK-FACTORS; NERVES; THYROIDECTOMY; MICROSCOPY; DIAGNOSIS;
D O I：
10.1364/BOE.3.001880
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Iatrogenic nerve damage is a leading cause of morbidity associated with many common surgical procedures. Complications arising from these injuries may result in loss of function and/or sensation, muscle atrophy, and chronic neuropathy. Fluorescence image-guided surgery offers a potential solution for avoiding intraoperative nerve damage by highlighting nerves that are otherwise difficult to visualize. In this work we present the development of a single camera, dual-mode laparoscope that provides near simultaneous display of white-light and fluorescence images of nerves. The capability of the instrumentation is demonstrated through imaging several types of in situ rat nerves via a nerve specific contrast agent. Full color white light and high brightness fluorescence images and video of nerves as small as 100 mu m in diameter are presented. (C) 2012 Optical Society of America
引用
收藏
页码：1880 / 1890
页数：11
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