Dual-mode laparoscopic fluorescence image-guided surgery using a single camera

被引：21

作者：

Gray, Daniel C. ^{[1
]}

Kim, Evgenia M. ^{[1
]}

Cotero, Victoria E. ^{[1
]}

Bajaj, Anshika ^{[1
]}

Staudinger, V. Paul ^{[1
]}

Hehir, Cristina A. Tan ^{[1
]}

Yazdanfar, Siavash ^{[1
]}

机构：

[1] GE Global Res, Niskayuna, NY 12309 USA

来源：

BIOMEDICAL OPTICS EXPRESS | 2012年 / 3卷 / 08期

关键词：

NEAR-INFRARED FLUORESCENCE; INTRAOPERATIVE ELECTRICAL-STIMULATION; IN-VIVO; PROSTATE-CANCER; CARDIAC-SURGERY; RISK-FACTORS; NERVES; THYROIDECTOMY; MICROSCOPY; DIAGNOSIS;

D O I：

10.1364/BOE.3.001880

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Iatrogenic nerve damage is a leading cause of morbidity associated with many common surgical procedures. Complications arising from these injuries may result in loss of function and/or sensation, muscle atrophy, and chronic neuropathy. Fluorescence image-guided surgery offers a potential solution for avoiding intraoperative nerve damage by highlighting nerves that are otherwise difficult to visualize. In this work we present the development of a single camera, dual-mode laparoscope that provides near simultaneous display of white-light and fluorescence images of nerves. The capability of the instrumentation is demonstrated through imaging several types of in situ rat nerves via a nerve specific contrast agent. Full color white light and high brightness fluorescence images and video of nerves as small as 100 mu m in diameter are presented. (C) 2012 Optical Society of America

引用

页码：1880 / 1890

页数：11

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