Discovery of imidazopyridine and imidazopyridazine inhibitors of PI3K

被引:0
|
作者
Han, Wooseok [1 ]
Pecchi, Sabina [1 ]
Burger, Matthew [1 ]
Lan, Jiong [1 ]
Smith, Aaron [1 ]
Knapp, Mark [1 ]
Huh, Kay [1 ]
De Menezes, Daniel Lopes [1 ]
Jansen, Johanna [1 ]
Merritt, Hanne [1 ]
Kaufman, Susan [1 ]
Voliva, Charles [1 ]
机构
[1] Novartis Inst Biomed Res, Emeryville, CA 94608 USA
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
42-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Discovery of novel quinazoline derivatives as potent PI3Kδ inhibitors with high selectivity
    Teng, Yu
    Li, Xinyu
    Ren, Shengnan
    Cheng, Yu
    Xi, Kun
    Shen, Hongtao
    Ma, Wenzhuo
    Luo, Guoshun
    Xiang, Hua
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 208
  • [32] Discovery of novel and potent PARP/PI3K dual inhibitors for the treatment of cancer
    Wu, Zhengyang
    Bai, Ying
    Jin, Jiaming
    Jiang, Teng
    Shen, Hui
    Ju, Qiurong
    Zhu, Qihua
    Xu, Yungen
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 217
  • [33] PI3K Inhibitors in Cardiovascular Disease
    Eisenreich, Andreas
    Rauch, Ursula
    CARDIOVASCULAR THERAPEUTICS, 2011, 29 (01) : 29 - 36
  • [34] Horizons broaden for PI3Kδ inhibitors
    Katie Kingwell
    Nature Reviews Drug Discovery, 2014, 13 : 573 - 573
  • [35] Designing selective PI3K inhibitors
    Crunkhorn, Sarah
    NATURE REVIEWS DRUG DISCOVERY, 2010, 9 (02) : 105 - 105
  • [36] Designing selective PI3K inhibitors
    Sarah Crunkhorn
    Nature Reviews Drug Discovery, 2010, 9 : 105 - 105
  • [37] Horizons broaden for PI3Kδ inhibitors
    Kingwell, Katie
    NATURE REVIEWS DRUG DISCOVERY, 2014, 13 (08) : 573 - 573
  • [38] Novel inhibitors of the PI3K family
    Carnero, Amancio
    EXPERT OPINION ON INVESTIGATIONAL DRUGS, 2009, 18 (09) : 1265 - 1277
  • [39] Cardiovascular toxicity of PI3Kα inhibitors
    Sadasivan, Chandu
    Zhabyeyev, Pavel
    Labib, Dina
    White, James A.
    Paterson, D. Ian
    Oudit, Gavin Y.
    CLINICAL SCIENCE, 2020, 134 (19) : 2595 - 2622
  • [40] PI3Kα Inhibitors That Inhibit Metastasis
    Schmidt-Kittler, Oleg
    Zhu, Jiuxiang
    Yang, Jian
    Liu, Guosheng
    Hendricks, William
    Lengauer, Christoph
    Gabelli, Sandra B.
    Kinzler, Kenneth W.
    Vogelstein, Bert
    Huso, David L.
    Zhou, Shibin
    ONCOTARGET, 2010, 1 (05) : 339 - 348