Results of a placebo-controlled double blind randomised trial to investigate the efficacy of rifaximin-alpha versus placebo in improving systemic inflammation in patients with cirrhosis and chronic hepatic encephalopathy (RIFSYS Trial)

被引:1
|
作者
Patel, V. [1 ]
Mcphail, M. J. W. [1 ]
Zamalloa, A. [1 ]
Stoy, S. [1 ,2 ]
Vijay, G. M. [1 ]
Huang, X. [1 ]
Rogers, G. [3 ]
Choo, J. [3 ]
Edwards, L. [1 ]
Gray, E. [1 ]
Woodhouse, C. [1 ]
Gencer, S. [4 ]
Coen, M. [4 ]
Wendon, J. [1 ]
Bruce, K. [5 ]
Shawcross, D. [1 ]
机构
[1] Kings Coll London, Fac Life Sci & Med, Sch Immunol & Microbial Sci, James Black Ctr,Liver Sci, 1st Floor, London, England
[2] Aarhus Univ Hosp, Dept Gastroenterol & Hepatol, Aarhus, Denmark
[3] South Australian Hlth & Med Res Inst, Microbiome Res, Adelaide, SA, Australia
[4] Imperial Coll London, Dept Surg & Canc, Div Computat & Syst Med, Biomol Med, London, England
[5] Kings Coll London, Inst Pharmaceut Sci, 5th Floor Franklin Wilkins Bldg, London, England
关键词
D O I
10.1016/S0168-8278(18)30432-X
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
LBP-005
引用
收藏
页码:S107 / S108
页数:2
相关论文
共 50 条
  • [31] Rifaximin Reduces the Risk of Hospitalizations in Patients with Previous Episodes of Hepatic Encephalopathy: Results from a Phase 3 Placebo-Controlled Trial
    Neff, Guy
    Leevy, Carroll B.
    Frederick, Todd
    Merchant, Kunal
    Huang, Shirley
    Shaw, Audrey L.
    Forbes, William P.
    GASTROENTEROLOGY, 2009, 136 (05) : A11 - A12
  • [32] Efficacy and Safety of Tofacitinib in Ankylosing Spondylitis: A Randomised, Double-blind, Placebo-controlled Trial
    Harish, B., V
    Sahoo, Rasmi Ranjan
    Gochhait, Samanyoya
    Patro, Pradeepta Sekhar
    INDIAN JOURNAL OF RHEUMATOLOGY, 2025, 20 (01) : 27 - 34
  • [33] Efficacy of microbial cell preparation in improving chronic constipation: A randomized, double-blind, placebo-controlled trial
    Jayasimhan, Sanmugapriya
    Yap, Ning-Yi
    Roest, Yvonne
    Rajandram, Retnagowri
    Chin, Kin-Fah
    CLINICAL NUTRITION, 2013, 32 (06) : 928 - 934
  • [34] Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
    Athauda, Dilan
    Maclagan, Kate
    Skene, Simon S.
    Bajwa-Joseph, Martha
    Letchford, Dawn
    Chowdhury, Kashfia
    Hibbert, Steve
    Budnik, Natalia
    Zampedri, Luca
    Dickson, John
    Li, Yazhou
    Aviles-Olmos, Iciar
    Warner, Thomas T.
    Limousin, Patricia
    Lees, Andrew J.
    Greig, Nigel H.
    Tebbs, Susan
    Foltynie, Thomas
    LANCET, 2017, 390 (10103): : 1664 - 1675
  • [35] Temporary sympathectomy in chronic refractory angina: a randomised, double-blind, placebo-controlled trial
    Denby, Christine
    Groves, David G.
    Eleuteri, Antonio
    Tsang, Hoo Kee
    Leach, Austin
    Hammond, Clare
    Bridson, John D.
    Fisher, Michael
    Elt, Matthew
    Laflin, Robert
    Fisher, Anthony C.
    BRITISH JOURNAL OF PAIN, 2015, 9 (03) : 142 - 148
  • [36] A double-blind randomized placebo-controlled trial of albumin in outpatients with hepatic encephalopathy: HEAL study
    Fagan, Andrew
    Gavis, Edith A.
    Gallagher, Mary Leslie
    Mousel, Travis
    Davis, Brian
    Puri, Puneet
    Sterling, Richard K.
    Luketic, Velimir A.
    Lee, Hannah
    Matherly, Scott C.
    Sanyal, Arun J.
    Stravitz, R. Todd
    Patel, Vaishali
    Siddiqui, Mohammad S.
    Asgharpour, Amon
    Fuchs, Michael
    Thacker, Leroy
    Bajaj, Jasmohan S.
    JOURNAL OF HEPATOLOGY, 2023, 78 (02) : 312 - 321
  • [37] Safety and efficacy of thalidomide in patients with POEMS syndrome: a multicentre, randomised, double-blind, placebo-controlled trial
    Misawa, Sonoko
    Sato, Yasunori
    Katayama, Kanako
    Nagashima, Kengo
    Aoyagi, Reiko
    Sekiguchi, Yukari
    Sobue, Gen
    Koike, Haruki
    Yabe, Ichiro
    Sasaki, Hidenao
    Watanabe, Osamu
    Takashima, Hiroshi
    Nishizawa, Masatoyo
    Kawachi, Izumi
    Kusunoki, Susumu
    Mitsui, Yoshiyuki
    Kikuchi, Seiji
    Nakashima, Ichiro
    Ikeda, Shu-ichi
    Kohara, Nobuo
    Kanda, Takashi
    Kira, Jun-ichi
    Hanaoka, Hideki
    Kuwabara, Satoshi
    LANCET NEUROLOGY, 2016, 15 (11): : 1129 - 1137
  • [38] Efficacy of Echinacea purpurea in patients with a common cold -: A placebo-controlled, randomised, double-blind clinical trial
    Schulten, B
    Bulitta, M
    Ballering-Brühl, B
    Köster, U
    Schäfer, M
    ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 2001, 51 (07): : 563 - 568
  • [39] A RANDOMIZED TRIPLE BLIND, PLACEBO- CONTROLLED TRIAL TO DETERMINE EFFECTIVENESS OF RIFAXIMIN IN PREVENTING HEPATIC ENCEPHALOPATHY IN PATIENTS WITH CHRONIC LIVER DISEASE
    Aqeel, Abdur Rehman
    Butt, Binyamin
    Naveed, Hira
    Arshad, Ali
    INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 5 (04): : 2728 - 2732
  • [40] Dose-finding trial of tolvaptan in liver cirrhosis patients with hepatic edema: A randomized, double-blind, placebo-controlled trial
    Okita, Kiwamu
    Kawazoe, Seiji
    Hasebe, Chitomi
    Kajimura, Kozo
    Kaneko, Akira
    Okada, Mitsuru
    Sakaida, Isao
    HEPATOLOGY RESEARCH, 2014, 44 (01) : 83 - 91