Regioselective palladium-catalyzed intramolecular oxidative aminofluorination of unactivated alkenes

被引:64
|
作者
Wu, Tao [1 ]
Cheng, Jiashun [1 ]
Chen, Pinhong [1 ]
Liu, Guosheng [1 ]
机构
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
关键词
FLUORINATED HETEROCYCLES; REDUCTIVE ELIMINATION; EFFICIENT SYNTHESIS; FLUORIDE; BONDS; BENZOQUINONE; SELECTFLUOR; CYCLIZATION; AMIDATION; COMPLEXES;
D O I
10.1039/c3cc44711a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel Pd-catalyzed regioselective intramolecular aminofluorination of unactivated alkenes has been developed, which is an efficient method for the synthesis of a variety of monofluoromethylated nitrogen-containing heterocycles.
引用
收藏
页码:8707 / 8709
页数:3
相关论文
共 50 条
  • [41] Palladium-Catalyzed Perfluoroalkylative Carbonylation of Unactivated Alkenes: Access to β-Perfluoroalkyl Esters
    Zhang, Youcan
    Geng, Hui-Qing
    Wu, Xiao-Feng
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (45) : 24292 - 24298
  • [42] Palladium-Catalyzed Dehydrogenative Coupling Reaction of Terminal Alkynes with Unactivated Alkenes
    Yada, Akira
    Nishi, Shoki
    Sato, Yuta
    Ichinoseki, Sakina
    Murakami, Masahiro
    JOURNAL OF THE CHINESE CHEMICAL SOCIETY, 2018, 65 (01) : 117 - 121
  • [43] Palladium-catalyzed regioselective oxidative amination of alkenes: an efficient route to the synthesis of pyrrolocoumarin and pyrroloquinolone derivatives
    Majumdar, K. C.
    Samanta, Srikanta
    Nandi, Raj Kumar
    Chattopadhyay, Buddhadeb
    TETRAHEDRON LETTERS, 2010, 51 (29) : 3807 - 3810
  • [44] Copper-Catalyzed Intramolecular Oxidative Amination of Unactivated Internal Alkenes
    Xiong, Peng
    Xu, Fan
    Qian, Xiang-Yang
    Yohannes, Yared
    Song, Jinshuai
    Lu, Xin
    Xu, Hai-Chao
    CHEMISTRY-A EUROPEAN JOURNAL, 2016, 22 (13) : 4379 - 4383
  • [45] Palladium-Catalyzed Intermolecular Polarity-Mismatched Addition of Unactivated Alkyl Radicals to Unactivated Alkenes
    Wu, Xiaojin
    Xiao, Guanlin
    Ding, Yalan
    Zhan, Ying
    Zhao, Yao
    Chen, Rizhi
    Loh, Teck-Peng
    ACS CATALYSIS, 2020, 10 (23) : 14107 - 14116
  • [46] Controllable access to trifluoromethyl-containing indoles and indolines: palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides
    Yang, Hefei
    Le-Cheng Wang
    Zhang, Yu
    Zheng, Dongling
    Chen, Zhengkai
    Xiao-Feng Wu
    CHEMICAL SCIENCE, 2022, 13 (12) : 3526 - 3532
  • [47] Silver-catalyzed radical aminofluorination of unactivated alkenes in aqueous media
    Li, C. (clig@mail.sioc.ac.cn), 1600, American Chemical Society (135):
  • [48] Silver-Catalyzed Radical Aminofluorination of Unactivated Alkenes in Aqueous Media
    Li, Zhaodong
    Song, Liyan
    Li, Chaozhong
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2013, 135 (12) : 4640 - 4643
  • [49] Intramolecular Oxidative Palladium-Catalyzed Amination Involving Double C-H Functionalization of Unactivated Olefins
    Broggini, Gianluigi
    Borelli, Tea
    Giofre, Sabrina
    Mazza, Alberto
    SYNTHESIS-STUTTGART, 2017, 49 (13): : 2803 - 2818
  • [50] ORGN 424-Palladium-catalyzed intramolecular diamination and chloroamination of unactivated alkenes
    Sibbald, Paul A.
    Cochran, Brian M.
    Michael, Forrest E.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 234