The histone deacetylase inhibitor LBH589 sensitizes pancreatic cancer cells to TRAIL-induced apoptosis through induction of c-FLIP degradation

被引：0
|
作者：
Kauh, John
Fan, Songqing
Yang, Lily
Khuri, Fadlo R.
Sun, Shi-Yong
机构：
来源：
CANCER RESEARCH | 2010年 / 70卷
关键词：
D O I：
10.1158/1538-7445.AM10-203
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
203
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Histone Deacetylase Inhibitors Sensitize TRAIL-Induced Apoptosis in Colon Cancer Cells
    Zhang, Baojie
    Liu, Bin
    Chen, Deng
    Setroikromo, Rita
    Haisma, Hidde J.
    Quax, Wim J.
    CANCERS, 2019, 11 (05)
  • [22] Metformin sensitizes human bladder cancer cells to TRAIL-induced apoptosis through mTOR/S6K1-mediated downregulation of c-FLIP
    Zhang, Tao
    Wang, Xinyang
    He, Dalin
    Jin, Xunbo
    Guo, Peng
    ANTI-CANCER DRUGS, 2014, 25 (08) : 887 - 897
  • [23] Berberine sensitizes TRAIL-induced apoptosis through proteasome-mediated downregulation of c-FLIP and Mcl-1 proteins
    Lee, Sung-Jun
    Noh, Hyo-Jeong
    Sung, Eon-Gi
    Song, In-Hwan
    Kim, Joo-Young
    Kwon, Taeg Kyu
    Lee, Tae-Jin
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2011, 38 (02) : 485 - 492
  • [24] Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor dependent human lung cancer cells
    Haura, E.
    Edwards, A.
    Bhalla, K.
    EJC SUPPLEMENTS, 2006, 4 (12): : 182 - 183
  • [25] Histone deacetylase inhibitor (HDACi) LBH589 interference with androgen receptor expression transcriptional activity in prostate cancer cells.
    Thelen, Paul
    Ringert, Rolf-Hermann
    Strauss, Arne
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [26] Knockdown of MTDH Sensitizes Endometrial Cancer Cells to Cell Death Induction by Death Receptor Ligand TRAIL and HDAC Inhibitor LBH589 Co-Treatment
    Meng, Xiangbing
    Brachova, Pavla
    Yang, Shujie
    Xiong, Zhi
    Zhang, Yuping
    Thiel, Kristina W.
    Leslie, Kimberly K.
    PLOS ONE, 2011, 6 (06):
  • [27] Protein expression of c-FLIP(L) is assoicated with resistance to trail-induced apoptosis in prostate cancer
    Olumi, AF
    Zhang, XP
    San Francisco, IF
    Dewolf, WC
    Jin, TG
    Khosravi-Far, R
    JOURNAL OF UROLOGY, 2003, 169 (04): : 214 - 214
  • [28] The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP
    Um, Hee Jung
    Oh, Jung Hwa
    Kim, Yoon-Nyun
    Choi, Yung Hyun
    Kim, Sang Hyun
    Park, Jong-Wook
    Kwon, Taeg Kyu
    CHEMICO-BIOLOGICAL INTERACTIONS, 2010, 186 (01) : 36 - 42
  • [29] Histone Deacetylase Inhibitor LBH589 (Panobinostat) Suppresses the Activated-NFκB Pathway in Acquired Aromatase Inhibitor Resistant Breast Cancer Cells
    Kubo, M.
    Kanaya, N.
    Liu, Z.
    Chen, S.
    CANCER RESEARCH, 2011, 71
  • [30] Effect of the histone deacetylase inhibitor LBH589 against epidermal growth factor receptor-dependent human lung cancer cells
    Edwards, Arthur
    Li, Jiannong
    Atadja, Peter
    Bhalla, Kapil
    Haura, Eric B.
    MOLECULAR CANCER THERAPEUTICS, 2007, 6 (09) : 2515 - 2524
12345