The histone deacetylase inhibitor LBH589 sensitizes pancreatic cancer cells to TRAIL-induced apoptosis through induction of c-FLIP degradation

被引：0
|
作者：
Kauh, John
Fan, Songqing
Yang, Lily
Khuri, Fadlo R.
Sun, Shi-Yong
机构：
来源：
CANCER RESEARCH | 2010年 / 70卷
关键词：
D O I：
10.1158/1538-7445.AM10-203
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
203
引用
收藏
页数：2
相关论文
共 50 条
  • [11] Knockdown of MADD and c-FLIP overcomes resistance to TRAIL-induced apoptosis in ovarian cancer cells
    Li, Liang-Cheng
    Jayaram, Shankar
    Ganesh, Lakshmy
    Qian, Lixia
    Rotmensch, Jacob
    Maker, Ajay V.
    Prabhakar, Bellur S.
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2011, 205 (04) : 362.e12 - 362.e25
  • [12] Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat)
    Kubo, Makoto
    Kanaya, Noriko
    Petrossian, Karineh
    Ye, Jingjing
    Warden, Charles
    Liu, Zheng
    Nishimura, Reiki
    Osako, Tomofumi
    Okido, Masayuki
    Shimada, Kazuo
    Takahashi, Masato
    Chu, Peiguo
    Yuan, Yate-Ching
    Chen, Shiuan
    BREAST CANCER RESEARCH AND TREATMENT, 2013, 137 (01) : 93 - 107
  • [13] Antimycin A sensitizes cells to TRAIL-induced apoptosis through upregulation of DR5 and downregulation of c-FLIP and Bcl-2
    Lee, Sung-Jun
    Kim, Eun-Ae
    Song, Kyoung Seob
    Kim, Min-Jae
    Lee, Dae Hyung
    Kwon, Taeg Kyu
    Lee, Tae-Jin
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2012, 41 (04) : 1425 - 1430
  • [14] Antimycin A Sensitizes TRAIL-induced Apoptosis Through Down-regulation of C-FLIP and Bcl-2 Proteins
    Lee, S. J.
    EUROPEAN JOURNAL OF CANCER, 2011, 47 : S104 - S104
  • [15] An inducible pathway for degradation of FLIP protein sensitizes tumor cells to TRAIL-induced apoptosis
    Kim, Y
    Suh, N
    Sporn, M
    Reed, JC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (25) : 22320 - 22329
  • [16] The Histone Deacetylase Inhibitor Trichostatin A Sensitizes Human Renal Carcinoma Cells to TRAIL-Induced Apoptosis through Down-Regulation of c-FLIPL
    Han, Min Ho
    Park, Cheol
    Kwon, Taek Kyu
    Kim, Gi-Young
    Kim, Wun-Jae
    Hong, Sang Hoon
    Yoo, Young Hyun
    Choi, Yung Hyun
    BIOMOLECULES & THERAPEUTICS, 2015, 23 (01) : 31 - 38
  • [17] Inhibition of the proliferation of acquired aromatase inhibitor-resistant breast cancer cells by histone deacetylase inhibitor LBH589 (panobinostat)
    Makoto Kubo
    Noriko Kanaya
    Karineh Petrossian
    Jingjing Ye
    Charles Warden
    Zheng Liu
    Reiki Nishimura
    Tomofumi Osako
    Masayuki Okido
    Kazuo Shimada
    Masato Takahashi
    Peiguo Chu
    Yate-Ching Yuan
    Shiuan Chen
    Breast Cancer Research and Treatment, 2013, 137 : 93 - 107
  • [18] Molecular Mechanism of the Cell Death Induced by the Histone Deacetylase Pan Inhibitor LBH589 (Panobinostat) in Wilms Tumor Cells
    Tao Yan-Fang
    Li Zhi-Heng
    Xu Li-Xiao
    Fang Fang
    Lu Jun
    Li Gang
    Cao Lan
    Wang Na-Na
    Du Xiao-Juan
    Sun Li-Chao
    Zhao Wen-Li
    Xiao Pei-Fang
    Zhao He
    Su Guang-Hao
    Li Yan-Hong
    Li Yi-Ping
    Xu Yun-Yun
    Zhou Hui-Ting
    Wu Yi
    Jin Mei-Fang
    Liu Lin
    Ni Jian
    Hu Shao-Yan
    Zhu Xue-Ming
    Feng Xing
    Wang Jian
    Pan Jian
    PLOS ONE, 2015, 10 (07):
  • [19] Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells (vol 19, pg 2237, 2007)
    Wang, Peng
    Zhang, Jing
    Bellail, Anita
    Jiang, Wen
    Hugh, Judith
    Kneteman, Norman M.
    Hao, Chunhai
    CELLULAR SIGNALLING, 2008, 20 (01) : 268 - 268
  • [20] The short splice form of Casper/c-FLIP is a major cellular inhibitor of TRAIL-induced apoptosis
    Bin, LH
    Li, XY
    Xu, LG
    Shu, HB
    FEBS LETTERS, 2002, 510 (1-2) : 37 - 40
12345