Antioxidant activity and spectroscopic data of isoxanthohomol oxime and related compounds

被引：23
|
作者：
Potaniec, Bartlomiej [1 ]
Grabarczyk, Malgorzata [1 ]
Stompor, Monika [1 ]
Szumny, Antoni [1 ]
Zielinski, Pawel [1 ]
Zolnierczyk, Anna Katarzyna [1 ]
Aniol, Miroslaw [1 ]
机构：
[1] Wroclaw Univ Environm & Life Sci, Fac Food Sci, Dept Chem, Norwida 25-27, PL-50375 Wroclaw, Poland
来源：
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2014年 / 118卷
关键词：
Isoxanthohumol oxime; Antioxidant activity; DPPH method; Synergism; NMR-IR-UV spectra; HUMULUS-LUPULUS L; 8-PRENYLNARINGENIN; CAPACITY; HOPS;
D O I：
10.1016/j.saa.2013.09.018
中图分类号：
O433 [光谱学];
学科分类号：
0703 ; 070302 ;
摘要：
Oximes of isoxanthohumol (IXN), naringenin (N) and flavanone (FL) were synthesized with yields of 88-95% and their antioxidant activity was evaluated using the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) method. Although naringenin oxime (NOX) and flavanone oxime (FLUX) did not have any significant antioxidant effect (EC50 = 2.21 mM and 78.7 mM, respectively), isoxanthohumol oxime (IXNOX) showed a strong antioxidant activity (EC50 = 0.0411 mM), comparable to the activity of ascorbic acid (EC50 = 0.0181 mM). The structure of new compound IXNOX was established using H-1 NMR, C-13 NMR, IR and UV-VIS spectroscopy, by comparison to IXN, NOX and FLUX. (C) 2013 Elsevier B.V. All rights reserved.
引用
收藏
页码：716 / 723
页数：8
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