Antioxidant activity and spectroscopic data of isoxanthohomol oxime and related compounds

被引：23

作者：

Potaniec, Bartlomiej ^{[1
]}

Grabarczyk, Malgorzata ^{[1
]}

Stompor, Monika ^{[1
]}

Szumny, Antoni ^{[1
]}

Zielinski, Pawel ^{[1
]}

Zolnierczyk, Anna Katarzyna ^{[1
]}

Aniol, Miroslaw ^{[1
]}

机构：

[1] Wroclaw Univ Environm & Life Sci, Fac Food Sci, Dept Chem, Norwida 25-27, PL-50375 Wroclaw, Poland

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2014年 / 118卷

关键词：

Isoxanthohumol oxime; Antioxidant activity; DPPH method; Synergism; NMR-IR-UV spectra; HUMULUS-LUPULUS L; 8-PRENYLNARINGENIN; CAPACITY; HOPS;

D O I：

10.1016/j.saa.2013.09.018

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Oximes of isoxanthohumol (IXN), naringenin (N) and flavanone (FL) were synthesized with yields of 88-95% and their antioxidant activity was evaluated using the 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) method. Although naringenin oxime (NOX) and flavanone oxime (FLUX) did not have any significant antioxidant effect (EC50 = 2.21 mM and 78.7 mM, respectively), isoxanthohumol oxime (IXNOX) showed a strong antioxidant activity (EC50 = 0.0411 mM), comparable to the activity of ascorbic acid (EC50 = 0.0181 mM). The structure of new compound IXNOX was established using H-1 NMR, C-13 NMR, IR and UV-VIS spectroscopy, by comparison to IXN, NOX and FLUX. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：716 / 723

页数：8

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