The regiospecific c-benzylation of heterocyclic ketene aminals with ethyl 2-(bromomethyl)benzoate:: A simple route to 1H-1midazo[1,2-b][2]benzazepin-5-one derivatives

被引：0

作者：

Xu, ZH ^{[1
]}

Jie, YF ^{[1
]}

Wang, MX ^{[1
]}

Huang, ZT ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Chem, Ctr Mol Sci, Beijing 100080, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2002年 / 04期

关键词：

heterocyclic ketene aminals; ethyl 2-(bromomethyl)benzoate; 1H-imidazo[1,2-b][2]benzazepin-5-one;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heterocyclic ketene aminals reacted with ethyl 2-(bromomethyl)benzoate in refluxing acetonitrile to afford the C-benzylated products that underwent intramolecular cyclocondensation reaction to produce epsilon-lactam fused heterocyclic compounds. The heterocyclic ring size effect on the reaction was discussed.

引用

页码：523 / 527

页数：5

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