Synthesis of ethyl 2-methyl-4-aryl-5-oxo-1H, 4H-indeno [1,2-b] dihydropyridine-3-carboxylates

被引：0
|
作者：
Edayadulla, N. [1 ]
Ramesh, P. [1 ]
机构：
[1] Madurai Kamaraj Univ, Sch Med, Dept Nat Prod Chem, Madurai 625021, Tamil Nadu, India
来源：
INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 16卷 / 04期
关键词：
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Ethyl 2-methyl-4-aryl-5-oxo-1H, 4H-indeno [1,2-b] dihydropyridine-3-carboxylates 4a-h have been synthesized from indane-1,3-dione and aromatic aldehydes in the presence of ethyl acetoacetate, piperidine and ammonium acetate by Hantzsch four component multicentre procedure. These compounds are expected to have anti hypertensive activity.
引用
收藏
页码：371 / 374
页数：4
相关论文
共 50 条
  • [1] Synthesis and crystal structures of 2-methyl-4-aryl-5-oxo-5H-indeno [1,2-b] pyridine carboxylate derivatives
    Ramesh Pandian
    Edayadulla Naushad
    Vinodhkumar Vijayakumar
    Günther H Peters
    Ponnuswamy Mondikalipudur Nanjappagounder
    Chemistry Central Journal, 8
  • [2] Synthesis and crystal structures of 2-methyl-4-aryl-5-oxo-5H-indeno [1,2-b] pyridine carboxylate derivatives
    Pandian, Ramesh
    Naushad, Edayadulla
    Vijayakumar, Vinodhkumar
    Peters, Guenther H.
    Nanjappagounder, Ponnuswamy Mondikalipudur
    CHEMISTRY CENTRAL JOURNAL, 2014, 8
  • [3] ETHYL ETHERS OF 1,4-DIHYDROPYRIDINE-3,5-DIHYDRO-1H-INDENO[1,2-B]PYRIDINE-3-CARBOTHIONIC AND 2-METHYL-4-ARYL-5-OXO-4,5-DIHYDRO-1H-INDENO[1,2-B]PYRIDINE-3-CARBOTHIONIC ACIDS
    VIGANTE, BA
    OZOLS, YY
    DUBUR, GY
    BELASH, YM
    BEILIS, YI
    KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1984, (02): : 210 - 216
  • [4] CHEMISTRY OF INDENOTHIOPHENES .2. 4H-INDENO 1,2-B!THIOPHENE AND 8H-INDENO 1,2-C!THIOPHENE
    MACDOWEL.DW
    JEFFRIES, AT
    JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (04): : 871 - &
  • [5] SYNTHESIS AND ALKYLATION OF 4-ARYL-5-OXO-1H-2,3,4,5-TETRAHYDROINDENO[1,2-b]PYRIDINES
    Stupnikova, S.
    Petushkova, E.
    Tanajev, D.
    Lusis, V.
    Muceniece, D.
    CHEMISTRY OF HETEROCYCLIC COMPOUNDS, 2010, 46 (07) : 859 - 867
  • [6] Synthesis and alkylation of 4-aryl-5-oxo-1h-2,3,4,5-tetrahydroindeno[1,2-b]pyridines*
    S. Stupnikova
    E. Petushkova
    D. Tanajev
    V. Lusis
    D. Muceniece
    Chemistry of Heterocyclic Compounds, 2010, 46 : 859 - 867
  • [7] Green Aspect for Multicomponent Synthesis of Spiro[4H-indeno[1,2-b]pyridine-4,3-[3H]indoles]
    Dige, Nilam C.
    Pore, Dattaprasad M.
    SYNTHETIC COMMUNICATIONS, 2015, 45 (21) : 2498 - 2510
  • [8] A New Four-Component Reaction for the Synthesis of Spiro[4H-indeno[1,2-b]pyridine-4,3′-[3H]indoles]
    Feiz, Afsaneh
    Shakibaei, Ghazaleh Imani
    Yasaei, Zahra
    Khavasi, Hamid Reza
    Bazgir, Ayoob
    HELVETICA CHIMICA ACTA, 2011, 94 (09) : 1628 - 1637
  • [9] CHEMISTRY OF INDENOTHIOPHENES .3. METALATION OF 3-BENZYLTHIOPHENE AND AN ALTERNATIVE SYNTHESIS OF 4H-INDENO[1,2-B]THIOPHENE-4-CARBOXYLIC ACID
    MACDOWELL, DW
    JEFFRIES, AT
    JOURNAL OF ORGANIC CHEMISTRY, 1971, 36 (08): : 1053 - +
  • [10] Synthesis and Properties of Ethyl 1-Aryl-5-methyl4-[1-(phenylhydrazinylidene)ethyl]-1H-pyrazole-3-carboxylates
    Potopnyk, M. A.
    Matiichuk, V. S.
    Obushak, M. D.
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2017, 53 (01) : 62 - 65
12345