Chiron approach for the synthesis of (1S,2R,5R,7S)-2-hydroxy-exo-brevicomin

被引：17
|
作者：
Gautam, D [1 ]
Kumar, DN [1 ]
Rao, BV [1 ]
机构：
[1] Indian Inst Chem Technol, Organ Div 3, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 05期
关键词：
D O I：
10.1016/j.tetasy.2006.02.020
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
(1S,2R,5R,7S)-2-Hydroxy-exo-brevicomin ent-1 was synthesized from 1,2;5,6-di-O-isopropylidene-(D)-glucose in seven steps. The key reaction in our synthesis is the formation of bicyclic ketal 7 under acid mediated acetal exchange of a 1,2-acetonide Of D-glucose derivative 6. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：819 / 821
页数：3
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