Neurosarcoidosis: Clinical Features, Diagnosis, and Management

被引：6

作者：

Schwendimann, Robert N. ^{[1
]}

Harris, Meghan K. ^{[1
]}

Elliott, Debra G. ^{[1
]}

Menon, Uma ^{[1
]}

Gonzalez-Toledo, Eduardo ^{[1
,2
]}

Zivadinov, Robert ^{[3
]}

Pressly, Thomas A. ^{[4
,5
]}

Kelley, Roger E. ^{[1
]}

Hoque, Romy ^{[1
]}

Fowler, Marjorie ^{[6
]}

Maghzi, Amir H. ^{[7
]}

Etemadifar, Masoud ^{[7
]}

Saadatnia, Mohammad ^{[7
]}

Minagar, Alireza ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Dept Neurol, Shreveport, LA 71130 USA

[2] Louisiana State Univ, Hlth Sci Ctr, Dept Radiol, Shreveport, LA 71130 USA

[3] SUNY Buffalo, Sch Med & Biomed Sci, Jacobs Neurol Inst, Buffalo Neuroimaging Anal Ctr,Dept Neurol, Buffalo, NY 14260 USA

[4] Louisiana State Univ, Hlth Sci Ctr, Dept Med, Div Rheumatol, Shreveport, LA 71130 USA

[5] Shriners Hosp Crippled Children, Juvenile Arthrit Ctr, Shreveport, LA USA

[6] Louisiana State Univ, Hlth Sci Ctr, Dept Pathol, Shreveport, LA 71130 USA

[7] Isfahan Univ Med Sci, Dept Neurol, Esfahan, Iran

来源：

AMERICAN JOURNAL OF THERAPEUTICS | 2013年 / 20卷 / 03期

关键词：

neurosarcoidosis; gallium scan; CD4(+)/CD8(+) ratio; tumor necrosis factor; immunosuppressive therapy; ALPHA PRODUCTION; SARCOIDOSIS; PENTOXIFYLLINE; MANIFESTATIONS;

D O I：

10.1097/MJT.0b013e31818637ef

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Sarcoidosis is a multisystemic granulomatous disease, which uncommonly affects nervous system. However, when present, it may affect both central and peripheral nervous systems and potentially mimics other chronic diseases of the nervous system. Pathogenesis of neurosarcoidosis remains largely unknown, and its diagnosis and management pose serious challenges to clinicians. Early diagnosis and aggressive treatment of neurosarcoidosis are necessary to produce satisfactory clinical outcomes. This review discusses clinical manifestations, current diagnostic studies, and currently available modalities for management of neurosarcoidosis.

引用

页码：292 / 299

页数：8

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