A dual-emission and large Stokes shift fluorescence probe for real-time discrimination of ROS/RNS and imaging in live cells

被引：106
|
作者：
Guo, Ting [1 ]
Cui, Lei [1 ]
Shen, Jiaoning [1 ]
Wang, Rui [1 ]
Zhu, Weiping [1 ]
Xu, Yufang [1 ]
Qian, Xuhong [1 ]
机构：
[1] E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2013年 / 49卷 / 18期
基金：
国家高技术研究发展计划(863计划);
关键词：
HYPOCHLOROUS-ACID; REACTIVE OXYGEN; NITRIC-OXIDE; MYELOPEROXIDASE; PEROXYNITRITE; SUPEROXIDE; BIOLOGY; STRESS; DESIGN;
D O I：
10.1039/c3cc38471c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel dual-emission fluorescence probe has been developed for specific and sensitive detection of hypochlorite (ClO-). Upon addition of ClO-, significant changes in fluorescence emission intensity at two discrete wavelengths were observed. Meanwhile OONO- led to only a single-channel fluorescence enhancement. This feature makes it a clear advantage in distinguishing ClO-, RNS from other ROS.
引用
收藏
页码：1862 / 1864
页数：3
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