CuCl2/TBHP-mediated direct chlorooxidation of indoles

被引：21
|
作者：
Wang, Huifei [1 ]
Liu, Dong [1 ]
Chen, Huiyu [1 ]
Li, Jing [1 ]
Wang, David Zhigang [1 ]
机构：
[1] Peking Univ, Shenzhen Grad Sch, Key Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China
来源：
TETRAHEDRON | 2015年 / 71卷 / 38期
基金：
美国国家科学基金会;
关键词：
CuCl2/TBHP; Chlorooxidation; Indoles; H BOND ACTIVATION; 3,3-DISUBSTITUTED OXINDOLES; CHLORINATION; CONSTRUCTION; 3-BROMOOXINDOLES; EFFICIENT; CARBON; 3-HALOOXINDOLES; DERIVATIVES; ALKYLATION;
D O I：
10.1016/j.tet.2015.05.065
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
CuCl2/TBHP-mediated direct chlorooxidation of indole derivatives under simple aerobic conditions was reported, leading to facile preparations of a range of 3,3-disubstituted 3-chlorooxindoles in good yields and selectivities. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7073 / 7076
页数：4
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