CuCl2/TBHP-mediated direct chlorooxidation of indoles

被引：21
|
作者：
Wang, Huifei [1 ]
Liu, Dong [1 ]
Chen, Huiyu [1 ]
Li, Jing [1 ]
Wang, David Zhigang [1 ]
机构：
[1] Peking Univ, Shenzhen Grad Sch, Key Lab Chem Genom, Sch Chem Biol & Biotechnol, Shenzhen 518055, Peoples R China
来源：
TETRAHEDRON | 2015年 / 71卷 / 38期
基金：
美国国家科学基金会;
关键词：
CuCl2/TBHP; Chlorooxidation; Indoles; H BOND ACTIVATION; 3,3-DISUBSTITUTED OXINDOLES; CHLORINATION; CONSTRUCTION; 3-BROMOOXINDOLES; EFFICIENT; CARBON; 3-HALOOXINDOLES; DERIVATIVES; ALKYLATION;
D O I：
10.1016/j.tet.2015.05.065
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
CuCl2/TBHP-mediated direct chlorooxidation of indole derivatives under simple aerobic conditions was reported, leading to facile preparations of a range of 3,3-disubstituted 3-chlorooxindoles in good yields and selectivities. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码：7073 / 7076
页数：4
相关论文
共 50 条
  • [31] I2/TBHP-mediated tandem cyclization and oxidation reaction: Facile access to 2,5-disubstituted oxazoles
    Guo, Xin
    Liu, Xianyan
    Li, Chonglong
    Jiang, Zhibo
    Nan, Zedong
    Liu, Yafeng
    TETRAHEDRON LETTERS, 2022, 112
  • [32] A novel CuCl2/BIL catalyst for direct oxidation of alcohol to acid at ambient temperature
    Karthikeyan, Parasuraman
    Aswar, Sachin Arunrao
    Muskawar, Prashant Narayan
    Bhagat, Pundlik Rambhau
    Kumar, S. Senthil
    CATALYSIS COMMUNICATIONS, 2012, 26 : 189 - 193
  • [33] Direct amination of azoles using CuCl2 complexes of amines under mild conditions
    Xu, Juan
    Li, Jiarong
    Wei, Zhen
    Zhang, Qi
    Shi, Daxin
    RSC ADVANCES, 2013, 3 (25) : 9622 - 9624
  • [34] I2/TBHP-mediated oxidative cascade cyclization of vinyl azide and benzylamine to construct 2,5-disubstituted oxazoles
    Pothireddy, Mohanreddy
    Chatterjee, Rana
    Penke, Vijaya Babu
    Dandela, Rambabu
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 21 (27) : 5521 - 5526
  • [35] Reactions of triazacyclohexanes with CuCl2:: Surprising formation of a dimer between two [CuCl2]- ions with an unsupported cuprophilic attraction
    Köhn, RD
    Seifert, G
    Pan, ZD
    Mahon, MF
    Kociok-Köhn, G
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (07) : 793 - 796
  • [36] Positron annihilation in polyvinylalcohol doped with CuCl2
    Mohamed, HFM
    Ito, Y
    ElSayed, AMA
    AbdelHady, EE
    POLYMER, 1996, 37 (09) : 1529 - 1533
  • [37] I2/TBHP-mediated oxidative coupling of ketones and toluene derivatives: a facile method for the preparation of α-benzoyloxy ketones
    Chen, Cui
    Liu, Weibing
    Zhou, Peng
    Liu, Hailing
    RSC ADVANCES, 2017, 7 (33): : 20394 - 20397
  • [38] Synthesis of fused oxazole-containing coumarin derivatives via oxidative cross coupling reaction using a combination of CuCl2 and TBHP
    Belal, Md
    Khan, Abu T.
    RSC ADVANCES, 2016, 6 (23) : 18891 - 18894
  • [39] TBHP-mediated C-H thiolation of tetrahydrofuran with disulfides promoted by catalytic amounts of Na2CO3
    Tao, Li-Ming
    Liu, Wen-Qi
    Li, Chuan-Hua
    Liu, Hui
    JOURNAL OF CHEMICAL RESEARCH, 2014, (05) : 280 - 282
  • [40] STM STUDY OF CUCL2 INTERCALATED IN GRAPHITE
    PAPPAS, RA
    HUNT, ER
    ULLOA, SE
    ULTRAMICROSCOPY, 1992, 42 : 679 - 682
12345