Acremonium kiliense: Case Report and Review of Published Studies

被引:16
|
作者
Camplesi Junior, Milton [1 ]
Arantes, Adriano de Moraes [2 ]
Silva, Hildene Meneses [3 ]
Costa, Carolina Rodrigues [3 ]
Rodrigues Silva, Maria do Rosario [3 ]
机构
[1] Univ Paulista UNIP Goias, Goiania, Go, Brazil
[2] Hosp Araujo Jorge, Assoc Combate Canc Estado Goias, Goiania, Go, Brazil
[3] Univ Fed Goias UFG, Inst Patol Trop & Saude Publ, BR-74605050 Goiania, Go, Brazil
关键词
Acremonium kiliense; Hematopoietic stem cell transplant; Voriconazole; FUNGAL-INFECTIONS; STRICTUM INFECTION; EPIDEMIOLOGY; PERITONITIS; FUNGEMIA;
D O I
10.1007/s11046-013-9700-x
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Changes in the spectrum of clinically important fungal infection have been observed in recent years. Acremonium species has been responsible for eumycotic mycetomas but has also been increasingly implicated in systemic fungal diseases. A case of Acremonium kiliense fungemia with proven involvement of the lungs in an allogeneic hematopoietic stem cell patient is reported. A high-resolution computed tomography scan of the lungs showed nodules in both lungs. Multiple cultures of blood demonstrated narrow septate hyphae, cylindrical conidia, and solitary tapering phialides and microconidia that remained grouped in slimy heads. The isolate was identified as A. kiliense based on its morphological characteristics and DNA sequence analysis. Susceptibility testing of the clinical isolate was performed to four antifungal agents. Amphotericin B, fluconazole and itraconazole were found to be inactive in vitro against the isolate; however, it was found to be sensitive to voriconazole. This last drug was indicated, and a high-resolution computed tomography scan of the lungs was normal after 10 days. One year later, the patient was free of symptoms and her blood culture was negative for fungi. Thus, voriconazole was effective in treatment for life-threatening A. kiliense infections. In this work, we performed an overview of worldwide clinical infections caused by A. kiliense.
引用
收藏
页码:417 / 421
页数:5
相关论文
共 50 条
  • [31] Primary cutaneous rhabdomyosarcoma: Case report and review of published work
    Kim, Yoon Seob
    Lee, Ji Hyun
    Lee, Jun Young
    Park, Young Min
    JOURNAL OF DERMATOLOGY, 2015, 42 (10): : 1014 - 1015
  • [32] Systemic sclerosis with sarcoidosis: Case report and review of the published work
    Senda, Satoko
    Igawa, Ken
    Nishioka, Megumi
    Murota, Hiroyuki
    Katayama, Ichiro
    JOURNAL OF DERMATOLOGY, 2014, 41 (05): : 421 - 423
  • [33] Trigeminal trophic syndrome: Report of a case and review of the published work
    Sawada, Takahiro
    Asai, Jun
    Nomiyama, Tomoko
    Masuda, Koji
    Takenaka, Hideya
    Katoh, Norito
    JOURNAL OF DERMATOLOGY, 2014, 41 (06): : 525 - 528
  • [34] Inflammatory pseudotumor of the spleen: A case report and review of published cases
    Ma, Zhen-Hai
    Tian, Xiao-Feng
    Ma, Jinhui
    Zhao, Yong-Fu
    ONCOLOGY LETTERS, 2013, 5 (06) : 1955 - 1957
  • [35] Xanthogranulomatous orchitis: Review of the published work, and report of one case
    Said, Shakhawan Hama Amin
    Abdalla, Rezhin Yaseen
    Aghaways, Ismaeel
    Abdullah, Ari Mohammed
    UROLOGY CASE REPORTS, 2019, 27
  • [36] Agranulocytosis Associated with Topiramate: A Case Report and Review of Published Cases
    Lohani, Saroj
    Tachamo, Niranjan
    Nazir, Salik
    Donato, Anthony
    CASE REPORTS IN HEMATOLOGY, 2018, 2018
  • [37] PULMONARY HISTOPLASMOSIS - REVIEW OF PUBLISHED CASES AND REPORT OF AN UNUSUAL CASE
    HODGSON, CH
    WEED, LA
    CLAGETT, OT
    JOURNAL OF THORACIC SURGERY, 1950, 20 (01): : 97 - 104
  • [38] Bullous pyoderma gangrenosum: A case report and review of the published work
    Sakiyama, Masayuki
    Kobayashi, Takashi
    Nagata, Yuiko
    Fujimoto, Norihiro
    Satoh, Takahiro
    Tajima, Shingo
    JOURNAL OF DERMATOLOGY, 2012, 39 (12): : 1010 - 1015
  • [39] ACCESSORY CARDIAC BRONCHUS - REPORT ON A CASE AND REVIEW OF THE PUBLISHED LITERATURE
    BEGUERY, P
    DENIES, JL
    DEVOOGD, A
    JOURNAL DE RADIOLOGIE, 1980, 61 (01): : 69 - 73