Structure-based discovery of non-peptidic small molecule inhibitors of Caspase-3

被引：0
|
作者：
Sakai, J
Yoshimori, A
Takasawa, R
Tanuma, SI
机构：
[1] Tokyo Univ Sci, Dept Biochem, Chiba, Japan
[2] Tokyo Univ Sci, Genome & Drug Res Ctr, Chiba, Japan
[3] Tokyo Univ Sci, Res Inst Biol Sci, Chiba, Japan
[4] Inst Theoret Med Inc, Tokyo, Japan
来源：
FEBS JOURNAL | 2005年 / 272卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：522 / 522
页数：1
相关论文
共 50 条
  • [21] Non-Peptidic Small Molecule Inhibitors Against Bcl-2 for Cancer Therapy
    Azmi, Asfar S.
    Mohammad, Ramzi M.
    JOURNAL OF CELLULAR PHYSIOLOGY, 2009, 218 (01) : 13 - 21
  • [22] Identification of potent and selective small-molecule inhibitors of caspase-3 through the use of extended tethering and structure-based drug design
    Choong, IC
    Lew, W
    Lee, D
    Pham, P
    Burdett, MT
    Lam, JW
    Wiesmann, C
    Luong, TN
    Fahr, B
    DeLano, WL
    McDowell, RS
    Allen, DA
    Erlanson, DA
    Gordon, EM
    O'Brien, T
    JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (23) : 5005 - 5022
  • [23] Non-peptidic hn protease inhibitors: Structure-based drug design of bis-sulfonamide dihydropyrones.
    Janakiraman, MN
    Watenpaugh, KD
    Tomich, PK
    Chong, KT
    Thaisrivongs, S
    Strohbach, JW
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1996, 212 : 207 - MEDI
  • [24] Discovery of novel non-peptidic and non-covalent small-molecule 3CLpro inhibitors as potential candidate for COVID-19 treatment
    Jiang, Zhidong
    Feng, Bo
    Zhang, Yumin
    Nie, Tianqing
    Liu, Hong
    Li, Jia
    Su, Haixia
    Zhang, Leike
    Zang, Yi
    Zhou, Yu
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 8 (01)
  • [25] Discovery of small molecule inhibitors of integrin αvβ3 through structure-based virtual screening
    Zhou, Yuan
    Peng, Hui
    Ji, Qing
    Qi, Jing
    Zhu, Zhenping
    Yang, Chunzheng
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (22) : 5878 - 5882
  • [26] Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model
    Borriello, Lucia
    Montes, Matthieu
    Lepelletier, Yves
    Leforban, Bertrand
    Liu, Wang-Qing
    Demange, Luc
    Delhomme, Brigitte
    Pavoni, Serena
    Jarray, Rafika
    Boucher, Jean Luc
    Dufour, Sylvie
    Hermine, Olivier
    Garbay, Christiane
    Hadj-Slimane, Reda
    Raynaud, Francoise
    CANCER LETTERS, 2014, 349 (02) : 120 - 127
  • [27] Structure-based discovery of novel small molecule Wnt/β-catenin signaling inhibitors
    Guzman, Stacy
    Nguyen, Alan
    De Lijser, Peter
    Patel, Nilay
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 253
  • [28] The discovery and optimization of potent non-peptidic matrix metalloprotease inhibitors.
    Benz, GHH
    Blake, P
    Brittelli, DR
    Bullock, WH
    Combs, KJ
    Dally, R
    Dixon, BR
    Ha, S
    Heald, S
    Housley, T
    Janis, R
    Katti, S
    Kluender, HC
    Maniglia, C
    Niedbala, M
    Perry, C
    Phelan, K
    Robbins, A
    Schneider, S
    Schoenleber, R
    Scott, W
    Tilton, R
    VanZandt, M
    Wilhelm, S
    Wolanin, D
    Wood, JE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1997, 214 : 111 - MEDI
  • [29] Structure-based design of non-peptidic cyclophilin ligands and their potential therapeutic utilities.
    Belyakov, S
    Hamilton, S
    Limburg, D
    Thomas, BE
    Vaal, M
    Wei, L
    Wilkinson, DE
    Fuller, M
    Connelly, M
    Steiner, JP
    Hamilton, GS
    Wu, YQ
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 225 : U219 - U219
  • [30] Structure-based design of non-peptidic pyridone aldehydes as inhibitors of interleukin-1 beta converting enzyme.
    Golec, JMC
    Mullican, MD
    Murcko, MA
    Wilson, KP
    Kay, DP
    Jones, SD
    Murdoch, R
    Bemis, GW
    Raybuck, SA
    Luong, YP
    Livingston, DJ
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (17) : 2181 - 2186
12345