Estimation of apoptosis in C6 glioma cells treated with antidepressants

被引：0
|
作者：
Spanova, A
Kovaru, H
Lisa, V
Lukasova, E
Rittich, B
机构：
[1] TECH UNIV,FAC CHEM,BRNO 63700,CZECH REPUBLIC
[2] ACAD SCI CZECH REPUBL,INST ANIM PHYSIOL & GENET,BRNO,CZECH REPUBLIC
[3] CHARLES UNIV,FAC MED 1,PRAGUE,CZECH REPUBLIC
[4] ACAD SCI CZECH REPUBL,INST PHYSIOL,PRAGUE,CZECH REPUBLIC
[5] ACAD SCI CZECH REPUBL,INST BIOPHYS,CS-61265 BRNO,CZECH REPUBLIC
来源：
PHYSIOLOGICAL RESEARCH | 1997年 / 46卷 / 02期
关键词：
glioma cells; antidepressants; DNA fragmentation; apoptosis; DNA FRAGMENTATION;
D O I：
暂无
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Gel electrophoresis of DNA was used for estimation of DNA changes caused in C6 glioma cells by treatment with psychotropic drugs (imipramine, amitryptiline and fluoxetine). Some discrete bands containing a population of short DNA fragments appeared after 1 and 5 days of cultivation. Apoptotic DNA breaks were verified at single cell level using the TUNEL test in cells treated with fluoxetine.
引用
收藏
页码：161 / 164
页数：4
相关论文
共 50 条
  • [31] Ultrastructure of nuclei of cisplatin-treated C6 glioma cells undergoing opoptosis
    Krajcí, D
    Mares, V
    Lisá, V
    Spanová, A
    Vorlícek, J
    EUROPEAN JOURNAL OF CELL BIOLOGY, 2000, 79 (05) : 365 - 376
  • [32] Nuclear envelope reaction in Cisplatin-treated C6 glioma cells.
    Krajci, D
    Mares, J
    Lisa, V
    ELECTRON MICROSCOPY 1998, VOL 4: BIOLOGICAL SCIENCES, 1998, : 833 - 834
  • [33] Identification of caveolae and caveolin in C6 glioma cells
    Silva, WI
    Maldonado, HM
    Lisanti, MP
    DeVellis, J
    Chompré, G
    Mayol, N
    Ortiz, M
    Velázquez, G
    Maldonado, A
    JOURNAL OF NEUROCHEMISTRY, 1999, 72 : S72 - S72
  • [34] Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells
    Klopocka, Wanda
    Korczynski, Jaroslaw
    Pomorski, Pawel
    GLIOMA SIGNALING, 2013, 986 : 103 - 119
  • [35] Cytoskeleton and Nucleotide Signaling in Glioma C6 Cells
    Klopocka, Wanda
    Korczynski, Jaroslaw
    Pomorski, Pawel
    GLIOMA SIGNALING, 2ND EDITION, 2020, 1202 : 109 - 128
  • [36] NO-mediated chemoresistance in C6 glioma cells
    Yang, DI
    Yin, JH
    Mishra, S
    Mishra, RAJ
    Hsu, CY
    NITRIC OXIDE: NOVEL ACTIONS, DELETERIOUS EFFECTS AND CLINICAL POTENTIAL, 2002, 962 : 8 - 17
  • [37] Mechanotransducing ion channels in C6 glioma cells
    Bowman, CL
    Lohr, JW
    GLIA, 1996, 18 (03) : 161 - 176
  • [38] Toxicity of compound A to C6 rat glioma cells
    Konat, GW
    Kofke, WA
    Miric, S
    METABOLIC BRAIN DISEASE, 2003, 18 (01) : 11 - 15
  • [39] Identification of caveolae and caveolin in C6 glioma cells
    Silva, WI
    Maldonado, HM
    Lisanti, MP
    Devellis, J
    Chompré, G
    Mayol, N
    Ortiz, M
    Velázquez, G
    Maldonado, A
    Montalvo, J
    INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 1999, 17 (07) : 705 - 714
  • [40] Effect of mtDNA depletion from C6 glioma cells and characteristics of the generated C6ρ0 cells
    Jin, Youcai
    Luan, Guangxiang
    Li, Ji
    Wang, Honglun
    Wang, Zhenhua
    Bai, Bo
    MOLECULAR MEDICINE REPORTS, 2021, 23 (04)
12345