CCR5Δ32, CCR2-64I, and SDF1-3′A polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

被引：5
|
作者：
Paz-y-Mino, C [1 ]
Morillo, SA
Celi, AP
Witte, T
Guijarro, MJM
Collantes, JC
Leone, PE
机构：
[1] Pontificia Univ Catolica Ecuador, Lab Genet Mol & Citogenet Humana, Escuela Ciencias Biol, Quito, Ecuador
[2] Pontificia Univ Catolica Ecuador, Area Genet & Biol Mol, Fac Med, Quito, Ecuador
[3] Hosp Gen Fuerzas Armadas, Clin SIDA, Quito, Ecuador
来源：
HUMAN BIOLOGY | 2005年 / 77卷 / 04期
关键词：
chemokines; disease prognosis; Ecuadorian population; HIV-1; infection; CCR5; Delta; 32; CCR2-64I; SDF1-3 ' A;
D O I：
10.1353/hub.2005.0068
中图分类号：
Q98 [人类学];
学科分类号：
030303 ;
摘要：
The aim of this study was to determine the allele frequencies of genetic variants CCR5 Delta 32, CCR2-64I, and SDF1-3'A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.
引用
收藏
页码：521 / 526
页数：6
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