CCR5Δ32, CCR2-64I, and SDF1-3′A polymorphisms related to resistance to HIV-1 infection and disease in the Ecuadorian population

被引：5

作者：

Paz-y-Mino, C ^{[1
]}

Morillo, SA

Celi, AP

Witte, T

Guijarro, MJM

Collantes, JC

Leone, PE

机构：

[1] Pontificia Univ Catolica Ecuador, Lab Genet Mol & Citogenet Humana, Escuela Ciencias Biol, Quito, Ecuador

[2] Pontificia Univ Catolica Ecuador, Area Genet & Biol Mol, Fac Med, Quito, Ecuador

[3] Hosp Gen Fuerzas Armadas, Clin SIDA, Quito, Ecuador

来源：

HUMAN BIOLOGY | 2005年 / 77卷 / 04期

关键词：

chemokines; disease prognosis; Ecuadorian population; HIV-1; infection; CCR5; Delta; 32; CCR2-64I; SDF1-3 ' A;

D O I：

10.1353/hub.2005.0068

中图分类号：

Q98 [人类学];

学科分类号：

030303 ;

摘要：

The aim of this study was to determine the allele frequencies of genetic variants CCR5 Delta 32, CCR2-64I, and SDF1-3'A (SDF1 801 A), which influence susceptibility to HIV-1 infection. We also investigated the effect of these variants on the general Ecuadoran population and on a group of HIV-infected individuals to determine the frequency of these genetics variants.

引用

页码：521 / 526

页数：6

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