A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

被引：22

作者：

Ye, Jia-Hai ^{[1
]}

Xu, Jing ^{[1
]}

Chen, Huachao ^{[2
]}

Bai, Yang ^{[2
]}

Zhang, Wenchao ^{[1
]}

He, Weijiang ^{[2
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China

[2] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China

来源：

RSC ADVANCES | 2014年 / 4卷 / 13期

关键词：

LIVING CELLS; AQUEOUS-SOLUTION; METAL COORDINATION; COPPER(II) IONS; RAPID DETECTION; ENERGY-TRANSFER; SENSOR; CHEMOSENSORS; PROBE; DERIVATIVES;

D O I：

10.1039/c3ra47157h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A BODIPY-based turn-on fluorescent probe 1 has been designed and synthesized for fluorescence detection of Cu2+ in aqueous media and imaging in living cells. The C=N bonds are selectively hydrolyzed by the reaction with Cu2+ to generate formyl-BODIPY. The favorable features of probe 1 towards Cu2+ include significant fluorescence enhancement (over 290-fold), high selectivity and low detection limit (0.1 mu M).

引用

页码：6691 / 6695

页数：5

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