A highly sensitive and selective turn-on fluorescent chemodosimeter for Cu2+ based on BODIPY and its application in bioimaging

被引：22
|
作者：
Ye, Jia-Hai [1 ]
Xu, Jing [1 ]
Chen, Huachao [2 ]
Bai, Yang [2 ]
Zhang, Wenchao [1 ]
He, Weijiang [2 ]
机构：
[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Jiangsu, Peoples R China
[2] Nanjing Univ, Sch Chem & Chem Engn, State Key Lab Coordinat Chem, Nanjing 210093, Jiangsu, Peoples R China
来源：
RSC ADVANCES | 2014年 / 4卷 / 13期
关键词：
LIVING CELLS; AQUEOUS-SOLUTION; METAL COORDINATION; COPPER(II) IONS; RAPID DETECTION; ENERGY-TRANSFER; SENSOR; CHEMOSENSORS; PROBE; DERIVATIVES;
D O I：
10.1039/c3ra47157h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A BODIPY-based turn-on fluorescent probe 1 has been designed and synthesized for fluorescence detection of Cu2+ in aqueous media and imaging in living cells. The C=N bonds are selectively hydrolyzed by the reaction with Cu2+ to generate formyl-BODIPY. The favorable features of probe 1 towards Cu2+ include significant fluorescence enhancement (over 290-fold), high selectivity and low detection limit (0.1 mu M).
引用
收藏
页码：6691 / 6695
页数：5
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