Structural and biological studies of new monomeric, tetrameric, and polymeric organotin(IV) esters of 3-(benzo[d][1,3]dioxol-4-yl)propanoic acid

被引：12
|
作者：
Hussain, Mukhtiar [1 ]
Zia-Ur-Rehman [1 ]
Ahmad, Muhammad Sheeraz [2 ]
Altaf, Muhammad [3 ]
Stoeckli-Evans, Helen [3 ]
Ali, Saqib [1 ]
机构：
[1] Quaid I Azam Univ, Dept Chem, Islamabad 45320, Pakistan
[2] Quaid I Azam Univ, Dept Biochem, Fac Biol Sci, Islamabad 45320, Pakistan
[3] Univ Neuchatel, Inst Phys, CH-2009 Neuchatel, Switzerland
来源：
JOURNAL OF COORDINATION CHEMISTRY | 2013年 / 66卷 / 05期
关键词：
Organotin(IV) carboxylates; Spectroscopic studies; X-ray crystallography; Biological screening; ANTITUMOR-ACTIVITY; CRYSTAL-STRUCTURE; COMPLEXES; DERIVATIVES; CHEMISTRY; DIORGANOTIN(IV); CARBOXYLATES;
D O I：
10.1080/00958972.2013.770845
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
Six new monomeric, tetrameric, and polymeric organotin(IV) derivatives of sodium 3-(benzo[d][1,3]dioxol-4-yl)propanoate (NaL) have been synthesized and characterized by various analytical techniques. These compounds show different structural behavior in solution and solid state as confirmed by NMR and X-ray single-crystal analysis. Antimicrobial and antitumor activities are mainly governed by diffusion, lipophilicity, geometry, and steric factors. The high antitumor and antifungal activities of some of these organotin compounds demand further investigations to commercialize them as new tin-based drugs.
引用
收藏
页码：868 / 880
页数：13
相关论文
共 50 条
  • [31] (E)-3-(6-Nitrobenzo[d][1,3]dioxol-5-yl)-1-(2,4,6-trimethoxyphenyl)prop-2-en-1-one
    Loghmani-Khouzani, Hossein
    Rahman, Noorsaadah Abdul
    Robinson, Ward T.
    Yaeghoobi, Marzieh
    Kia, Reza
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O2545 - +
  • [32] Synthesis of 2-amino-4-(2-ethoxybenzo[d][1,3]dioxol-5-yl)-4H-pyran-3-Carbonitrile Derivatives and Their Biological Evaluation
    Baitha, Amresh
    Gopinathan, Ajay
    Krishnan, Kartik
    Dabholkar, Vijay V.
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 2018, 55 (05) : 1189 - 1192
  • [33] (E)-1-(Benzo[d][1,3]dioxol-5-yl)-3-([2,2′-bithio-phen]-5-yl)prop-2-en-1-one: crystal structure, UV-Vis analysis and theoretical studies of a new π-conjugated chalcone
    Anizaim, Ainizatul Husna
    Zaini, Muhamad Fikri
    Laruna, Muhammad Adlan
    Razak, Ibrahim Abdul
    Arshad, Suhana
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2019, 75 : 632 - +
  • [34] (E)-1-(Benzo[d][1,3]dioxol-5-yl)-5,6,6-trimethylhept-4-en-3-one ( vol 2024, M1938, 2024)
    Rico-Molina, Mario
    Altarejos, Joaquin
    Salido, Sofia
    MOLBANK, 2025, 2025 (01)
  • [35] Fluoro Substituted Monomeric and Uni-Dimensional Polymeric Organotin(IV) Esters of (E)-4-oxo-4-((3-trifluoromethyl)phenyl)amino)but-2-enoic acid; Synthesis, Characterization and Their In vitro Inhibitory Studies
    ur-Rehman, Aziz
    Hussain, Mukhtiar
    Rauf, Abdul
    Tahir, Asif Ali
    Ali, Saqib
    JOURNAL OF INORGANIC AND ORGANOMETALLIC POLYMERS AND MATERIALS, 2012, 22 (04) : 699 - 708
  • [36] Fluoro Substituted Monomeric and Uni-Dimensional Polymeric Organotin(IV) Esters of (E)-4-oxo-4-((3-trifluoromethyl)phenyl)amino)but-2-enoic acid; Synthesis, Characterization and Their In vitro Inhibitory Studies
    Aziz ur-Rehman
    Mukhtiar Hussain
    Abdul Rauf
    Asif Ali Tahir
    Saqib Ali
    Journal of Inorganic and Organometallic Polymers and Materials, 2012, 22 : 699 - 708
  • [37] Synthesis and antioxidant evaluation of some heterocyclic candidates from 3-(1,3-diphenyl-1H-pyrazol-4-yl)-2-(4-oxo-4H-benzo[d][1,3]oxazin-2-yl)propenonitrile
    Ramadan, Sayed K.
    El-Ziaty, Ahmed K.
    El-Helw, Eman A. E.
    SYNTHETIC COMMUNICATIONS, 2021, 51 (08) : 1272 - 1283
  • [38] Comprehensive study of solvent effects on optical characteristics for novel pyrene-based chalcone compound: (E)-1-(benzo[d][1,3] dioxol-5-yl)-3-(pyren-1-yl)prop-2-en-1-one
    Alsaee, Saleh K.
    Mzwd, Elham
    Abu Bakar, Mohamad Aizat
    Samsuri, S. A. M.
    Ahmed, Naser M.
    Abdullah, Mundzir
    Razak, Ibrahim Abdul
    Arshad, Suhana
    OPTIK, 2023, 272
  • [39] α-Glucosidase inhibition activity and in silico study of 2-(benzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one, a synthetic derivative of flavone
    Meena, Surya N.
    Kumar, Ujjwal
    Naik, Mayuri M.
    Ghadi, Sanjeev C.
    Tilve, Santosh G.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 27 (12) : 2340 - 2344
  • [40] SYNTHESIS OF NEW 3-(BENZO [d] IMIDAZOL-2-YL AMINO)-2-(3-ARYL-1-PHENYL-1H-PYRAZOL-4-YL) THIAZOLIDIN-4-ONES
    Patil, Sharanabasappa B.
    Basha, N. Jeelan
    Goudgaon, N. M.
    INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY, 2010, 19 (03) : 307 - 308
12345