Anti-nutritional characteristics and mechanism of soybean agglutinin

被引:9
|
作者
Pan, Li [1 ]
Liu, Jiawei [1 ]
Farouk, Mohammed Hamdy [2 ]
Qin, Guixin [1 ]
Bao, Nan [1 ]
Zhao, Yuan [1 ]
Sun, Hui [1 ]
机构
[1] Jilin Agr Univ, Coll Anim Sci & Technol, Key Lab Anim Nutr & Feed Sci, Minist Educ,Key Lab Anim Prod Prod Qual & Secur, Changchun 130118, Peoples R China
[2] Al Azhar Univ, Fac Agr, Anim Prod Dept, Cairo 11884, Egypt
基金
中国国家自然科学基金;
关键词
Soybean agglutinin; Autophagy; Cell apoptosis; Anti-nutritional functions; Cell signaling; JUNCTION PROTEIN EXPRESSION; PROGRAMMED CELL-DEATH; PLANT-LECTINS; TRYPSIN-INHIBITORS; BINDING LECTIN; CONCANAVALIN-A; IN-VITRO; APOPTOSIS; AUTOPHAGY; DIGESTIBILITY;
D O I
10.32604/biocell.2021.014289
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Soybean agglutinin (SBA) is an important anti-nutritional factor in soybean. SBA can induce animal growth inhibition, cause pathological changes of intestinal tissue, and decrease in the immune system functioning. Recently, a great deal of research has been done on the effects of SBA on cell morphology, division, apoptosis, autophagy, as well as the correlated signal transduction pathway. This review mainly covers the chemical and biological characteristics of SBA, describes the multifaceted aspects of SBA anti-nutritional functions, and highlights the possible cellular and molecular mechanism of anti-nutritional effects of SBA. This review has important implications for the prevention and treatment of SBA-induced diseases, drug development, processing techniques of plant products, prevention of food-borne toxins, as well as human and animal health protection.
引用
收藏
页码:451 / 459
页数:9
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