SPME-GC-MS analysis of α-pyrrolidinovaleorophenone in blood in a fatal poisoning case

被引：56
|
作者：
Saito, Takeshi [1 ]
Namera, Akira [2 ]
Osawa, Motoki [3 ]
Aoki, Hiromichi [1 ]
Inokuchi, Sadaki [1 ]
机构：
[1] Tokai Univ, Dept Emergency & Crit Care Med, Sch Med, Isehara, Kanagawa 2591143, Japan
[2] Hiroshima Univ, Inst Biomed & Hlth Sci, Dept Forens Med, Minami Ku, Hiroshima 7348551, Japan
[3] Tokai Univ, Dept Forens Med, Sch Med, Isehara, Kanagawa 2591143, Japan
来源：
FORENSIC TOXICOLOGY | 2013年 / 31卷 / 02期
关键词：
alpha-Pyrrolidinovaleorophenone; Designer drug; Gas chromatography-mass spectrometry; Poisoning; DRUGS;
D O I：
10.1007/s11419-013-0183-8
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
We provided toxicological analytical support for a fatal case of abuse of alpha-pyrrolidinovaleorophenone (alpha-PVP). Solid-phase microextraction (SPME) and capillary gas chromatography coupled to mass spectrometry (GC-MS) was employed to quantify the drug in whole blood. The whole blood concentration of the drug in the heart was 486 ng/ml. This is the first report of alpha-PVP intoxication as ascertained by mass spectrometric identification of alpha-PVP in whole blood.
引用
收藏
页码：328 / 332
页数：5
相关论文
共 50 条
  • [21] Modifications of brewing parameters: Analysis of volatiles by SPME-GC-MS and hydrogen sulfide analysis in beer
    Benedict, Lucille
    Byrnes, Richard
    Ricardi, Aaron
    Qazi, Mariam
    Gregorich, Patrick
    Arris, Dominis
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2015, 249
  • [22] Analysis of Volatile Compounds in Fish Meal Based on SPME-GC-MS and Electronic Nose
    Li P.
    Niu Z.
    Zhu M.
    Shao K.
    Geng J.
    Li H.
    Nongye Jixie Xuebao/Transactions of the Chinese Society for Agricultural Machinery, 2020, 51 (07): : 397 - 405
  • [23] Trace analysis of UV filters and musks in living fish by in vivo SPME-GC-MS
    Iran Ocaña-Rios
    Araceli Peña-Alvarez
    Ignacio Zuñiga-Perez
    Elena Loeza-Fuentes
    Analytical and Bioanalytical Chemistry, 2019, 411 : 3209 - 3218
  • [24] Screening of air pollutants in Almaty city using SPME-GC-MS
    Kenessov, Bulat
    Baimatova, Nassiba
    Nauryzbayev, Mikhail
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2011, 242
  • [25] DEVELOPMENT OF A SPME-GC-MS METHOD FOR SPOILAGE DETECTION IN CASE OF PLUMS INOCULATED WITH PENICILLIUM EXPANSUM
    Sagi-Kiss, V.
    Fodor, P.
    ACTA ALIMENTARIA, 2011, 40 : 188 - 197
  • [26] Optimization of determination condition of volatile components in turbot by SPME-GC-MS
    Xu, Yongxia
    Liu, Ying
    Li, Xuepeng
    Li, Jianrong
    Zhao, Wei
    Li, Yujin
    Li, Jianrong, 1600, Chinese Institute of Food Science and Technology (14): : 233 - 238
  • [27] Uncertainty in the quantification of pentachlorophenol in wood processing wastewaters by SPME-GC-MS
    I. Brás
    N. Ratola
    A. Alves
    Journal of Analytical Chemistry, 2011, 66 : 756 - 762
  • [28] Citrus juice classification by SPME-GC-MS and electronic nose measurements
    Reinhard, Hans
    Sager, Fritz
    Zoller, Otmar
    LWT-FOOD SCIENCE AND TECHNOLOGY, 2008, 41 (10) : 1906 - 1912
  • [29] Analysis of Volatile Flavor Compounds of Sweet and Sour Spareribs Flavoring by SPME-GC-MS and GC-O
    Zhang, Yuyu (zhangyy2@163.com), 1600, Chinese Chamber of Commerce (38):
  • [30] Uncertainty in the quantification of pentachlorophenol in wood processing wastewaters by SPME-GC-MS
    Bras, I.
    Ratola, N.
    Alves, A.
    JOURNAL OF ANALYTICAL CHEMISTRY, 2011, 66 (08) : 756 - 762
12345