Astaxanthin inhibits TGF-β1-induced fibrogenic gene expression by inhibiting the activation of Smad3 and KLF-6 pathways in LX-2 and primary mouse hepatic stellate cells

被引：0
|
作者：
Yang, Yue [1 ]
Lee, Ji-Young [1 ]
机构：
[1] Univ Connecticut, Storrs, CT USA
来源：
FASEB JOURNAL | 2013年 / 27卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
32.3
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Interaction of ERK1/2 and Smad2/3 signaling pathways in TGF-β1-induced TIMP-3 expression in rat chondrocytes
    Wang, Xiang
    Zhu, Yanhui
    Tao, Hairong
    Jin, Chen
    Liu, Yonzhang
    Lu, Xiongwei
    Hu, Xiaopeng
    Fan, Cunyi
    ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 2014, 564 : 229 - 236
  • [42] PTPL1 suppresses lung cancer cell migration via inhibiting TGF-β1-induced activation of p38 MAPK and Smad 2/3 pathways and EMT
    Zhu, Ning
    Zhang, Xiu-juan
    Zou, Hai
    Zhang, Yuan-yuan
    Xia, Jing-wen
    Zhang, Peng
    Zhang, You-zhi
    Li, Jing
    Dong, Liang
    Wumaier, Gulinuer
    Li, Sheng-qing
    ACTA PHARMACOLOGICA SINICA, 2021, 42 (08) : 1280 - 1287
  • [43] PTPL1 suppresses lung cancer cell migration via inhibiting TGF-β1-induced activation of p38 MAPK and Smad 2/3 pathways and EMT
    Ning Zhu
    Xiu-juan Zhang
    Hai Zou
    Yuan-yuan Zhang
    Jing-wen Xia
    Peng Zhang
    You-zhi Zhang
    Jing Li
    Liang Dong
    Gulinuer Wumaier
    Sheng-qing Li
    Acta Pharmacologica Sinica, 2021, 42 : 1280 - 1287
  • [44] Astaxanthin Prevented and Reversed the Activation of Mouse Primary Hepatic Stellate Cells by Inhibiting the Myocyte Enhancer Factor 2-Dependent Expression of Histone Deacetylase 9
    Yang, Yue
    Bae, Minkyung
    Kim, Bohkyung
    Rudraiah, Swetha
    Manautou, Jose
    Park, Young-Ki
    Koo, Sung
    Lee, Ji-Young
    FASEB JOURNAL, 2015, 29
  • [45] Stachydrine inhibits TGF-β1-induced epithelial-mesenchymal transition in hepatocellular carcinoma cells through the TGF-β/Smad and PI3K/Akt/mTOR signaling pathways
    Chen, Xiangni
    Yan, Ning
    ANTI-CANCER DRUGS, 2021, 32 (08) : 786 - 792
  • [46] Role of cross-talk between the Smad2 and MAPK pathways in TGF-β1-induced collagen IV expression in mesangial cells
    Jiang, Weina
    Zhang, Yan
    Wu, Huijuan
    Zhang, Xin
    Gan, Hualei
    Sun, Jianyong
    Chen, Qi
    Guo, Muyi
    Zhang, Zhigang
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2010, 26 (04) : 571 - 576
  • [47] Platyconic Acid A, Platycodi Radix-Derived Saponin, Suppresses TGF-β1-Induced Activation of Hepatic Stellate Cells via Blocking SMAD and Activating the PPARγ Signaling Pathway
    Choi, Jae Ho
    Kim, Seul Mi
    Lee, Gi Ho
    Jin, Sun Woo
    Lee, Hyun Sun
    Chung, Young Chul
    Jeong, Hye Gwang
    CELLS, 2019, 8 (12)
  • [48] ANP signaling inhibits TGF-β-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells
    Li, Peng
    Oparil, Suzanne
    Novak, Lea
    Cao, Xu
    Shi, Weibin
    Lucas, Jason
    Chen, Yiu-Fai
    JOURNAL OF APPLIED PHYSIOLOGY, 2007, 102 (01) : 390 - 398
  • [49] Alpha Mangostin Inhibits the Proliferation and Activation of Acetaldehyde Induced Hepatic Stellate Cells through TGF-beta and ERK 1/2 Pathways
    Lestari, Novriantika
    Louisa, Melva
    Soetikno, Vivian
    Suwana, Averina Geffanie
    Ramadhan, Putra Andito
    Akmal, Taufiq
    Arozal, Andwawaimuli
    JOURNAL OF TOXICOLOGY, 2018, 2018
  • [50] Doxycycline Inhibits Tgf-β1-Induced Epithelial-Mesenchymal Transition And Migration Via Smad2/3 And P38 Pathways In Respiratory Epithelial Cells
    Lee, H. -M.
    Kang, J. -H.
    Park, J. -H.
    Kim, H. -J.
    Shin, J. -M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2016, 193
12345