Astaxanthin inhibits TGF-β1-induced fibrogenic gene expression by inhibiting the activation of Smad3 and KLF-6 pathways in LX-2 and primary mouse hepatic stellate cells

被引：0
|
作者：
Yang, Yue [1 ]
Lee, Ji-Young [1 ]
机构：
[1] Univ Connecticut, Storrs, CT USA
来源：
FASEB JOURNAL | 2013年 / 27卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
32.3
引用
收藏
页数：1
相关论文
共 50 条
  • [21] Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells
    Ming-ming Ni
    Tao Xu
    Ya-rui Wang
    Ying-hua He
    Qun Zhou
    Cheng Huang
    Xiao-ming Meng
    Jun Li
    Journal of Physiology and Biochemistry, 2016, 72 : 9 - 23
  • [22] Apigenin Alleviates Liver Fibrosis by Inhibiting Hepatic Stellate Cell Activation and Autophagy via TGF-β1/Smad3 and p38/PPARα Pathways
    Ji, Jie
    Yu, Qiang
    Dai, Weiqi
    Wu, Liwei
    Feng, Jiao
    Zheng, Yuanyuan
    Li, Yan
    Guo, Chuanyong
    PPAR RESEARCH, 2021, 2021
  • [23] Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells
    Ni, Ming-ming
    Xu, Tao
    Wang, Ya-rui
    He, Ying-hua
    Zhou, Qun
    Huang, Cheng
    Meng, Xiao-ming
    Li, Jun
    JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY, 2016, 72 (01) : 9 - 23
  • [24] KLF10 Inhibits TGF-β-Mediated Activation of Hepatic Stellate Cells via Suppression of ATF3 Expression
    Hwang, Soonjae
    Park, Sangbin
    Yaseen, Uzma
    Lee, Ho-Jae
    Cha, Ji-Young
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (16)
  • [25] Phillygenin Inhibits TGF-β1-induced Hepatic Stellate Cell Activation and Inflammation: Regulation of the Bax/Bcl-2 and Wnt/β-catenin Pathways
    Wang, Cheng
    Zhang, Shenglin
    Li, Yanzhi
    Gong, Lihong
    Yao, Chenhao
    Fu, Ke
    Li, Yunxia
    INFLAMMATION, 2024, 47 (04) : 1403 - 1422
  • [26] Paeonol alleviates CCl4-induced liver fibrosis through suppression of hepatic stellate cells activation via inhibiting the TGF-β/Smad3 signaling
    Wu, Shengwang
    Liu, Laicheng
    Yang, Sen
    Kuang, Ge
    Yin, Xinru
    Wang, Yuanyuan
    Xu, Fangzhi
    Xiong, Lingyi
    Zhang, Meixia
    Wan, Jingyuan
    Gong, Xia
    IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, 2019, 41 (03) : 438 - 445
  • [27] Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice
    Ping Huang
    Huihui Ma
    Yun Cao
    Tingzheng Zhan
    Tingting Zhang
    Xinyi Wang
    Yanan Zhang
    Jing Xu
    Chaoming Xia
    Parasites & Vectors, 15
  • [28] Activation of primary hepatic stellate cells and liver fibrosis induced by targeting TGF-β1/Smad signaling in schistosomiasis in mice
    Huang, Ping
    Ma, Huihui
    Cao, Yun
    Zhan, Tingzheng
    Zhang, Tingting
    Wang, Xinyi
    Zhang, Yanan
    Xu, Jing
    Xia, Chaoming
    PARASITES & VECTORS, 2022, 15 (01)
  • [29] Up‐regulation of FUT8 inhibits TGF-β1-induced activation of hepatic stellate cells during liver fibrogenesis
    Mengzhen Kuang
    Hao Wu
    Lan Hu
    Xinying Guo
    Daochuan He
    Bo Liu
    Mengqian Chen
    Jie Gu
    Jianxin Gu
    Xiaoqing Zeng
    Yuanyuan Ruan
    Glycoconjugate Journal, 2021, 38 : 77 - 87
  • [30] LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway
    Yang, Ya-ru
    Bu, Fang-tian
    Yang, Yang
    Li, Hao
    Huang, Cheng
    Meng, Xiao-ming
    Zhang, Lei
    Lv, Xiong-wen
    Li, Jun
    MOLECULAR IMMUNOLOGY, 2020, 126 : 31 - 39
12345