mTORC1 Drives the Spectrum of Pathology in Systemic JIA and Macrophage Activation Syndrome

被引:0
|
作者
Huang, Zhengping [1 ]
You, Xiaomeng [2 ]
Chen, Liang [3 ]
Du, Yan [3 ]
Brodeur, Kailey [3 ]
Wang, Qiang [3 ]
Sykes, David [4 ]
Chang, Margaret [5 ]
Charles, Julia [2 ]
Nigrovic, Peter [5 ]
Lee, Pui [5 ]
机构
[1] Guangdong Second Prov Hosp, Guangzhou, Peoples R China
[2] Brigham & Womens Hosp, Boston, MA USA
[3] Boston Childrens Hosp, Boston, MA USA
[4] Massachusetts Gen Hosp, Boston, MA USA
[5] Boston Childrens Hosp, Div Immunol, Boston, MA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
0004
引用
收藏
页码:7 / 9
页数:3
相关论文
共 50 条
  • [31] Dynamics of mTORC1 activation in response to amino acids
    Manifava, Maria
    Smith, Matthew
    Rotondo, Sergio
    Walker, Simon
    Niewczas, Izabella
    Zoncu, Roberto
    Clark, Jonathan
    Ktistakis, Nicholas T.
    ELIFE, 2016, 5
  • [32] mTORC1 activation in childhood ependymoma and response to sirolimus
    Bowers, Daniel C.
    Kucejova, Blanka
    Margraf, Linda
    Gargan, Lynn
    Brugarolas, James
    JOURNAL OF NEURO-ONCOLOGY, 2011, 103 (03) : 797 - 801
  • [33] The Activation of mTORC1 in Leukocytes of Patients with Cancer and Diabetes
    Vatseba, Tamara
    Sokolova, Liubov K.
    Pushkarev, Viktor V.
    Kovzun, Olena I.
    Pushkarev, Volodymir M.
    Tronko, Mykola D.
    DIABETES, 2019, 68
  • [34] Activation of mTORC1 in Collecting Ducts Causes Hyperkalemia
    Chen, Zhenguo
    Dong, Heling
    Jia, Chunhong
    Song, Qiancheng
    Chen, Juan
    Zhang, Yue
    Lai, Pinglin
    Fan, Xiaorong
    Zhou, Xuan
    Liu, Miao
    Lin, Jun
    Yang, Cuilan
    Li, Ming
    Gao, Tianming
    Bai, Xiaochun
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2014, 25 (03): : 534 - 545
  • [35] Remyelination in neuromyelitis optica spectrum disorder is promoted by edaravone through mTORC1 signaling activation
    Luo, Wenjing
    Xu, Huiming
    Xu, Li
    Jiang, Wei
    Chen, Chen
    Chang, Yanyu
    Liu, Chunxin
    Tian, Zhenming
    Qiu, Xiusheng
    Xie, Chichu
    Li, Xuejia
    Chen, Haijia
    Lai, Shuiqing
    Wu, Longjun
    Cui, Yaxiong
    Tang, Changyong
    Qiu, Wei
    GLIA, 2023, 71 (02) : 284 - 304
  • [36] mTORC1 activation in childhood ependymoma and response to sirolimus
    Daniel C. Bowers
    Blanka Kucejova
    Linda Margraf
    Lynn Gargan
    James Brugarolas
    Journal of Neuro-Oncology, 2011, 103 : 797 - 801
  • [37] Structural Insights into the Activation of mTORC1 on the Lysosomal Surface
    Park, Jin H.
    Lee, Gina
    Blenis, John
    TRENDS IN BIOCHEMICAL SCIENCES, 2020, 45 (05) : 367 - 369
  • [38] Connecting mTORC1 signaling to SREBP-1 activation
    Bakan, Inan
    Laplante, Mathieu
    CURRENT OPINION IN LIPIDOLOGY, 2012, 23 (03) : 226 - 234
  • [39] On the Rab again-the PATh to mTORC1 activation
    Gopaldass, Navin
    Rompf, Maria
    Mayer, Andreas
    EMBO REPORTS, 2013, 14 (05) : 398 - 399
  • [40] Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production
    Yael Riahi
    Aviram Kogot-Levin
    Liat Kadosh
    Bella Agranovich
    Assaf Malka
    Michael Assa
    Ron Piran
    Dana Avrahami
    Benjamin Glaser
    Eyal Gottlieb
    Fields Jackson
    Erol Cerasi
    Ernesto Bernal-Mizrachi
    Aharon Helman
    Gil Leibowitz
    Diabetologia, 2023, 66 : 1925 - 1942