On the Rab again-the PATh to mTORC1 activation

被引：1
|
作者：
Gopaldass, Navin [1 ]
Rompf, Maria [1 ]
Mayer, Andreas [1 ]
机构：
[1] Univ Lausanne, Dept Biochem, CH-1066 Epalinges, Switzerland
来源：
EMBO REPORTS | 2013年 / 14卷 / 05期
关键词：
AMINO-ACIDS;
D O I：
10.1038/embor.2013.48
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This month, Matsui and Fukuda report that Rab12 regulates autophagy indirectly by stimulating the constitutive degradation of the amino acid transporter PAT4. This negatively regulates mTORC1 and stimulates autophagy.
引用
收藏
页码：398 / 399
页数：2
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