Culcitiolides A-D, Four New Eremophilane-Type Sesquiterpene Derivatives from Senecio culcitioides

被引：0

作者：

Nozaki, Hiroshi ^{[1
]}

Hayashi, Ken-ichiro ^{[1
]}

Kawai, Mikiko ^{[2
]}

Mitsui, Taichi ^{[1
]}

Kido, Masahiro ^{[2
]}

Tani, Hiroyuki ^{[2
]}

Takaoka, Daisuke ^{[3
]}

Uno, Hidemitsu ^{[2
]}

Ohira, Susumu ^{[1
]}

Kuboki, Atsuto ^{[1
]}

Matsuura, Nobuyasu ^{[1
]}

机构：

[1] Okayama Univ Sci, Fac Sci, Dept Biol Chem, Okayama 7000005, Japan

[2] Ehime Univ, Grad Sch Sci & Engn, Matsuyama, Ehime 7908577, Japan

[3] Ehime Univ, Fac Gen Educ, Dept Chem, Matsuyama, Ehime 7908577, Japan

来源：

NATURAL PRODUCT COMMUNICATIONS | 2012年 / 7卷 / 04期

关键词：

Senecio culcitioides; Eremophilane; Culcitiolide A-D; Nuclear factor kappa B; NF-KAPPA-B; MEDICINAL-PLANTS; PROTEINS;

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Four new eremophilane-type sesquiterpenes, culcitiolides A-D, were isolated from the stem of Senecio culcitioides Sch. Bip (Asteraceae). Their structures were established by detailed 2D NMR spectroscopic and single-crystal X-ray experiments. These compounds were assessed for inhibitory activity against nuclear factor kappa B (NF-kappa B). Culcitiolides C and D at 20 mu M showed 97 and 100% inhibition of NF-kappa B activity, respectively.

引用

页码：427 / 430

页数：4

共 50 条

[41] Four new sesquiterpene derivatives from Dendrobium findlayanum
Yang Dan
Cheng Zhong-Quan
Zi Cheng-Ting
Yang Liu
Dong Fa-Wu
Hu Jiang-Miao
Zhou Jun
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 17 (12) : 900 - 905
[42] Four new sesquiterpene derivatives from Dendrobium findlayanum
YANG Dan
CHENG Zhong-Quan
ZI Cheng-Ting
YANG Liu
DONG Fa-Wu
HU Jiang-Miao
ZHOU Jun
Chinese Journal of Natural Medicines, 2019, 17 (12) : 900 - 905
[43] Cochliones A-D, four new tetrahydrochromanone derivatives from endophytic Cochliobolus sp.
Wang, Qi-Zhi
Ge, Hui-Ming
Zhang, Jie
Wu, Jun-Hua
Song, Yong-Chun
Zhang, Yu-Fei
Tan, Ren-Xiang
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2010, 12 (06) : 485 - 491
[44] New eremophilane-type sesquiterpenoids, eremoxylarins A and B from xylariaceous endophytic fungus YUA-026
Shiono, Y
Murayama, T
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2005, 60 (08): : 885 - 890
[45] New eremophilane-type sesquiterpenes and maleimide-bearing compounds from Carpesium abrotanoides L.
Wang, Lei
Jin, Guan
Tian, Li
Ebrahim, Weaam
Hoefert, Simon-Patrick
Janiak, Christoph
Chen, Jian-Feng
Guo, Zhi-Yong
Schaeberle, Till F.
Liu, Zhen
Cheng, Fan
Proksch, Peter
Zou, Kun
FITOTERAPIA, 2019, 138
[46] Rhodomyrtals A-D, four unusual phloroglucinol-sesquiterpene adducts from Rhodomyrtus psidioides
Shou, Qingyao
Smith, Joshua E.
Mon, Htwe
Brkljaca, Zlatko
Smith, Ana-Suncana
Smith, David M.
Griesser, Hans J.
Wohlmuth, Hans
RSC ADVANCES, 2014, 4 (26): : 13514 - 13517
[47] NATURALLY OCCURRING TERPENE DERIVATIVES .183. NEW BISABOLENE DERIVATIVES AND OTHER SESQUITERPENE DERIVATIVES FROM SENECIO-COCCINEIFLORUS AND SENECIO-OVIRENSIS
BOHLMANN, F
MAHANTA, PK
PHYTOCHEMISTRY, 1979, 18 (04) : 678 - 680
[48] Fluevirines A-D, four new securinega-type alkaloids from Flueggea virosa
Li, Xiao-Hui
Cao, Ming-Ming
Zhang, Yu
Li, Shun-Lin
Di, Ying-Tong
Hao, Xiao-Jiang
TETRAHEDRON LETTERS, 2014, 55 (44) : 6101 - 6104
[49] Xylariaopyrones A-D, four new antimicrobial α-pyrone derivatives from endophytic fungus Xylariales sp
Guo, Zhi-Yong
Lu, Li-Wen
Bao, Shang-Song
Liu, Cheng-Xiong
Deng, Zhang-Shuang
Cao, Fei
Liu, Shi-Ping
Zan, Kun
Proksch, Peter
PHYTOCHEMISTRY LETTERS, 2018, 28 : 98 - 103
[50] Dysidavarones A-D, New Sesquiterpene Quinones from the Marine Sponge Dysidea avara
Jiao, Wei-Hua
Huang, Xiao-Jun
Yang, Ji-Si
Yang, Fan
Piao, Shu-Jian
Gao, Hao
Li, Jia
Ye, Wen-Cai
Yao, Xin-Sheng
Chen, Wan-Sheng
Lin, Hou-Wen
ORGANIC LETTERS, 2012, 14 (01) : 202 - 205

← 1 2 3 4 5 →