Antidiabetic potential of Butea monosperma in rats

被引:55
|
作者
Somani, R
Kasture, S
Singhai, AK
机构
[1] NDMVPS, Coll Pharm, Nasik 422002, India
[2] Dr Hari Singh Gour Vishwavidyalaya, Dept Pharmaceut Sci, Sagar 470003, India
关键词
Butea monosperma; antihyperglycemic; antidiabetic activity;
D O I
10.1016/j.fitote.2005.11.003
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The antibyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced diabetic rats. Repeated oral treatment with BMEE (200 mg/kg/day) for 2 weeks significantly reduced blood glucose, serum cholesterol and improved HDL-cholesterol and albumin as compared to diabetic control group. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码:86 / 90
页数:5
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