Antidiabetic potential of Butea monosperma in rats

被引：55
|
作者：
Somani, R
Kasture, S
Singhai, AK
机构：
[1] NDMVPS, Coll Pharm, Nasik 422002, India
[2] Dr Hari Singh Gour Vishwavidyalaya, Dept Pharmaceut Sci, Sagar 470003, India
来源：
FITOTERAPIA | 2006年 / 77卷 / 02期
关键词：
Butea monosperma; antihyperglycemic; antidiabetic activity;
D O I：
10.1016/j.fitote.2005.11.003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The antibyperglycemic activity of the ethanolic extract of Butea monosperma (BMEE) was studied in glucose-loaded and alloxan-induced diabetic rats. Single dose treatment of BMEE (200 mg/kg, p.o.) significantly improved glucose tolerance and caused reduction in blood glucose level in alloxan-induced diabetic rats. Repeated oral treatment with BMEE (200 mg/kg/day) for 2 weeks significantly reduced blood glucose, serum cholesterol and improved HDL-cholesterol and albumin as compared to diabetic control group. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：86 / 90
页数：5
相关论文
共 50 条
  • [21] ANTIDIABETIC EFFECT OF A COMPOUND ETHANOLIC EXTRACT OF ANNONA SQUAMOSA, ECLIPTA ALBA, & BUTEA MONOSPERMA IN EXPERIMENTAL ANIMALS
    Gupta, Prashant
    Alok, Shashi
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2018, 9 (12): : 5485 - 5489
  • [22] Osteogenic activity of constituents from Butea monosperma
    Maurya, Rakesh
    Yadav, Dinesh K.
    Singh, Geetu
    Bhargavan, Biju
    Murthy, P. S. Narayana
    Sahai, Mahendra
    Singh, Man Mohan
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (03) : 610 - 613
  • [23] CHEMICAL EXAMINATION OF ROOT OF BUTEA-MONOSPERMA
    TANDON, SP
    TIWARI, KP
    SAXENA, VK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES, 1969, 39 : 237 - &
  • [24] In vitro antidiabetic activities of Myanmar medicinal plants: Cassia siamea Lam. and Butea monosperma Roxb.
    Thida, Mya
    Moe, The Su
    Chan, Khin Nyein
    Ei, Shun Lai
    Khai, Aye Aye
    INDIAN JOURNAL OF NATURAL PRODUCTS AND RESOURCES, 2022, 13 (04): : 483 - 490
  • [25] Seasonal variation in chlorophyll a fluorescence of Butea monosperma
    Meravi, Neelima
    Prajapati, Santosh Kumar
    BIOLOGICAL RHYTHM RESEARCH, 2020, 51 (06) : 751 - 758
  • [26] ANTIOXIDANT ACTIVITY OF FLAVONOIDAL CONTENT OF BUTEA MONOSPERMA
    Gupta, Piyush
    Mendhe, Bibhilesh B.
    Singh, Namrata
    Pande, Milind
    Pathak, Anupam
    Yadav, Sahadev
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2010, 1 (04): : 85 - 88
  • [27] Antinociceptive effect of Butea monosperma on vincristine-induced neuropathic pain model in rats
    Thiagarajan, Venkata Rathina Kumar
    Shanmugam, Palanichamy
    Krishnan, Uma Maheswari
    Muthuramans, Arunachalam
    Singhs, Nirmal
    TOXICOLOGY AND INDUSTRIAL HEALTH, 2013, 29 (01) : 3 - 13
  • [28] AN IMIDE FROM THE PODS OF BUTEA-MONOSPERMA
    GUHA, PK
    POI, R
    BHATTACHARYYA, A
    PHYTOCHEMISTRY, 1990, 29 (06) : 2017 - 2017
  • [29] The importance of Butea monosperma for the restoration of degraded lands
    Rai, Apurva
    Singh, Ashutosh Kumar
    Pandey, Vimal Chandra
    Ghosal, Nandita
    Singh, Nandita
    ECOLOGICAL ENGINEERING, 2016, 97 : 619 - 623
  • [30] Evaluation of protective effect of Butea monosperma (lam.) Taub in experimental hepatotoxicity in rats
    Gupta, Arti
    Sheth, N. R.
    Pandey, Sonia
    Yadav, Jitendra S.
    Shah, D. R.
    Vyas, B.
    Joshi, S.
    JOURNAL OF PHARMACOLOGY & PHARMACOTHERAPEUTICS, 2012, 3 (02) : 183 - +
12345