Artemisia annua L. extract ameliorates galactose-induced cognitive impairment in mice

被引：5
|
作者：
Kim, Mi Hye [1 ]
Seo, Ji Yeon [1 ]
Kim, Jong-Sang [1 ]
机构：
[1] Kyungpook Natl Univ, Sch Food Sci & Biotechnol BK21 Plus, Daegu 41566, South Korea
来源：
FOOD SCIENCE AND BIOTECHNOLOGY | 2015年 / 24卷 / 05期
关键词：
Artemisia annua; cognitive function; antioxidant enzymes; Morris water maze task; ALZHEIMERS-DISEASE; ACETYLCHOLINESTERASE ACTIVITY; NRF2-MEDIATED INDUCTION; DETOXIFYING ENZYMES; INULA-HELENIUM; PREVENTION; MECHANISMS; RAT;
D O I：
10.1007/s10068-015-0250-5
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Our previous study showed that Artemisia annua L. extract (AAE) exerted antioxidative effect in a mouse model. Therefore, we hypothesized that AAE could also protect against oxidative stress-induced cognitive impairment, such as memory loss. Oral feeding of an AAE-containing diet resulted in weak yet significant protection from galactose-induced memory impairment and hippocampal damage in mice. The AAE-induced amelioration was likely associated with the ability of AAE to induce antioxidant enzymes.
引用
收藏
页码：1901 / 1905
页数：5
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