Artemisia annua L. extract ameliorates galactose-induced cognitive impairment in mice

被引：5

作者：

Kim, Mi Hye ^{[1
]}

Seo, Ji Yeon ^{[1
]}

Kim, Jong-Sang ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Sch Food Sci & Biotechnol BK21 Plus, Daegu 41566, South Korea

来源：

FOOD SCIENCE AND BIOTECHNOLOGY | 2015年 / 24卷 / 05期

关键词：

Artemisia annua; cognitive function; antioxidant enzymes; Morris water maze task; ALZHEIMERS-DISEASE; ACETYLCHOLINESTERASE ACTIVITY; NRF2-MEDIATED INDUCTION; DETOXIFYING ENZYMES; INULA-HELENIUM; PREVENTION; MECHANISMS; RAT;

D O I：

10.1007/s10068-015-0250-5

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

Our previous study showed that Artemisia annua L. extract (AAE) exerted antioxidative effect in a mouse model. Therefore, we hypothesized that AAE could also protect against oxidative stress-induced cognitive impairment, such as memory loss. Oral feeding of an AAE-containing diet resulted in weak yet significant protection from galactose-induced memory impairment and hippocampal damage in mice. The AAE-induced amelioration was likely associated with the ability of AAE to induce antioxidant enzymes.

引用

页码：1901 / 1905

页数：5

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