PI3Kδ/γ Inhibitor Duvelisib Modulates Inflammatory Profile in Severe COVID-19 Patients: Results from a Randomized Placebo-Controlled Phase 2 Study

被引：0

作者：

Zhang, Hanwen ^{[1
]}

Wang, Shuhua ^{[1
]}

Rupji, Manali ^{[2
]}

Wu, Chenxi ^{[3
]}

Chandrasekaran, Sanjay ^{[4
]}

Funk, Christopher R. ^{[1
]}

King, Patrick J. ^{[5
]}

Kollipara, Saketh ^{[6
]}

Rao, Ishani ^{[6
]}

Ayanru, Esohe ^{[6
]}

Duffy, Julia ^{[7
]}

Kaplow, Roberta ^{[7
]}

Abousaud, Aseala ^{[8
]}

Mehta, Aneesh ^{[9
]}

Roback, John D. ^{[5
]}

Kalman, Daniel ^{[5
]}

Lyon, G. Marshall, III ^{[9
]}

Caridi-Scheible, Mark ^{[10
]}

Bisson, Gregory ^{[11
]}

Liu, Yuan ^{[2
]}

Coma, Silvia ^{[12
]}

Pachter, Jonathan A. ^{[12
]}

Giver, Cynthia R. ^{[1
]}

Waller, Edmund K. ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Dept Hematol & Med Oncol, Atlanta, GA 30322 USA

[2] Emory Univ, Winship Canc Inst, Dept Biostat & Bioinformat, Atlanta, GA 30322 USA

[3] Emory Univ, Sch Med, Dept Radiol & Imaging Sci, Atlanta, GA 30322 USA

[4] Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX 75390 USA

[5] Emory Univ, Sch Med, Dept Pathol & Lab Med, Atlanta, GA 30322 USA

[6] Emory Univ, Atlanta, GA 30322 USA

[7] Emory Univ Hosp, Emory Healthcare, 1364 Clifton Rd NE, Atlanta, GA 30322 USA

[8] Emory Healthcare, Atlanta, GA USA

[9] Emory Univ, Sch Med, Dept Infect Dis, Atlanta, GA 30322 USA

[10] Emory Univ, Sch Med, Crit Care Med, Atlanta, GA 30322 USA

[11] Univ Penn, Perelman Sch Med, Div Infect Dis, Dept Med, Philadelphia, PA 19104 USA

[12] Verastem Oncol, Needham, MA USA

来源：

BLOOD | 2022年 / 140卷

关键词：

D O I：

10.1182/blood-2022-165567

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：11187 / 11189

页数：3

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