The role of FDG PET-CT in differential diagnosis of pleural pathologies

被引:12
|
作者
Elboga, U. [1 ]
Yilmaz, M. [1 ]
Uyar, M. [2 ]
Celen, Y. Zeki [1 ]
Bakir, K. [3 ]
Dikensoy, O. [2 ]
机构
[1] Gaziantep Univ, Sch Med, Dept Nucl Med, Gaziantep, Turkey
[2] Gaziantep Univ, Sch Med, Dept Pulm Med, Gaziantep, Turkey
[3] Gaziantep Univ, Sch Med, Dept Pathol, Gaziantep, Turkey
来源
REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR | 2012年 / 31卷 / 04期
关键词
FDG PET-CT; Pleural thickening; Malignant pleural mesothelioma; POSITRON-EMISSION-TOMOGRAPHY; TREMOLITE ASBESTOS; MESOTHELIOMA; FEATURES; EXPOSURE; DISEASE;
D O I
10.1016/j.remn.2011.06.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective: This study has aimed to evaluate the impact of (F18) Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET-CT) in the differential diagnosis of malignant and benign pleural lesions in patients with suspected malignant pleural mesothelioma (MPM). Material and methods: Fifty patients (32 females, 18 males; age range 24-79 years) with pleural thickening, fluid, plaques or calcification on previous CT scan were examined with FDG PET-CT. PET-CT imaging was obtained 1 h after FOG injection. In 12 patients, delayed imaging from the thoracic region was performed 2 h after injection. FDG uptake was evaluated visually and semiquantitively using standardized uptake value (Soy). FOG PET-CT findings were compared with histopathologic diagnosis. Results: Thirty-nine patients had increased FOG uptake in pleural lesions but PET-CT results were negative in 11 patients. When compared with histopathological results in FDG positive group, 34 patients had MPM, 5 had benign pathology: in FDG negative group 8 patients had benign pathology, 3 had MPM. Of patients with delayed imaging, 9 showed increased SUV but 3 had a decreased SUV on delayed images. Increased SUV group had 4 MPM, 5 benign pathology (3 chronic granulomatous inflammation, 2 benign asbestotic plaque). Decreased SUV group all had benign pathology (fibrosis, chronic inflammation, myofibrosis). Discussion: FOG PET-CT is a useful imaging modality in differential diagnosis of malignant and benign pleural lesions. Delayed imaging seems to be useful if there is a decrease in SUV suggesting a benign pathology but does not seem to contribute to the differential diagnosis if the SUV is increased. (C) 2011 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
引用
收藏
页码:187 / 191
页数:5
相关论文
共 50 条
  • [41] Role of FDG PET-CT in the evaluation of extramedullary involvement in multiple myeloma
    Prakash, Sneha
    Sarswat, Sulochana
    Jaleel, Jasim
    Yadav, Divya
    Tripathy, Sarthak
    Shamim, Shamim Ahmed
    Damle, Nishikant
    Tripathi, Madhavi
    Kumar, Rakesh
    Bal, Chandrasekhar
    JOURNAL OF NUCLEAR MEDICINE, 2022, 63
  • [42] Role of FDG PET-CT in post therapy patients with uterine sarcomas
    Sharma, P.
    Singh, H.
    Jeph, S.
    Bal, C.
    Malhotra, A.
    Kumar, R.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2011, 38 : S370 - S370
  • [43] The Role of 18 FDG PET-CT in Evaluation of Unknown Primary Tumours
    Saidha N.K.
    Ganguly M.
    Sidhu H.S.
    Gupta S.
    Indian Journal of Surgical Oncology, 2013, 4 (3) : 236 - 241
  • [44] The Role of FDG PET/CT for the Diagnosis of Urothelial Cancer
    Nishiyama, T.
    Ashikari, A.
    Namitome, R.
    Yagi, Y.
    Kono, Y.
    Toya, K.
    Yorozu, A.
    Saito, S.
    UROLOGY, 2012, 80 (03) : S202 - S202
  • [45] A Review of the Role of FDG-PET/CT and PET/MRI in Malignant Pleural Mesothelioma
    Bural, Gonca
    Torigian, Drew
    Alavi, Abass
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [46] Cogan Syndrome: Differential Response to Biologic Agents and Role of PET-CT in the Increased Diagnosis of Aortitis
    Toz, Bahtiyar
    Erer, Burak
    Kamali, Sevil
    Tugal-Tutkun, Ilknur
    Ocal, Lale
    Gul, Ahmet
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [47] PET-CT evaluation of malignant pleural mesothelioma
    Gad, Youhanna
    Vattoth, Surjith
    McNamara, Michelle
    O'Malley, Janis
    JOURNAL OF NUCLEAR MEDICINE, 2010, 51
  • [48] Evaluation of 18FDG PET-CT in the Diagnosis of Endometriosis: A Prospective Study
    Fastrez, Maxime
    Nogarede, C.
    Tondeur, M.
    Sirtaine, N.
    Rozenberg, S.
    REPRODUCTIVE SCIENCES, 2011, 18 (06) : 540 - 544
  • [49] COGAN SYNDROME: DIFFERENTIAL RESPONSE TO BIOLOGIC AGENTS AND ROLE OF PET-CT IN THE INCREASED DIAGNOSIS OF AORTITIS
    Burak, Erer
    Bahtiyar, Toz
    Sevil, Kamali
    Ilknur, Tugal Tutkun
    Lale, Ocal
    Ahmet, Gul
    INTERNAL MEDICINE JOURNAL, 2016, 46 : 45 - 45
  • [50] COGAN SYNDROME: DIFFERENTIAL RESPONSE TO BIOLOGIC AGENTS AND ROLE OF PET-CT IN THE INCREASED DIAGNOSIS OF AORTITIS
    Toz, B.
    Erer, B.
    Kamali, S.
    Tugal-Tutkun, I.
    Ocal, L.
    Gul, A.
    ANNALS OF THE RHEUMATIC DISEASES, 2016, 75 : 1208 - 1209