The role of FDG PET-CT in differential diagnosis of pleural pathologies

被引:12
|
作者
Elboga, U. [1 ]
Yilmaz, M. [1 ]
Uyar, M. [2 ]
Celen, Y. Zeki [1 ]
Bakir, K. [3 ]
Dikensoy, O. [2 ]
机构
[1] Gaziantep Univ, Sch Med, Dept Nucl Med, Gaziantep, Turkey
[2] Gaziantep Univ, Sch Med, Dept Pulm Med, Gaziantep, Turkey
[3] Gaziantep Univ, Sch Med, Dept Pathol, Gaziantep, Turkey
来源
REVISTA ESPANOLA DE MEDICINA NUCLEAR E IMAGEN MOLECULAR | 2012年 / 31卷 / 04期
关键词
FDG PET-CT; Pleural thickening; Malignant pleural mesothelioma; POSITRON-EMISSION-TOMOGRAPHY; TREMOLITE ASBESTOS; MESOTHELIOMA; FEATURES; EXPOSURE; DISEASE;
D O I
10.1016/j.remn.2011.06.002
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objective: This study has aimed to evaluate the impact of (F18) Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (FDG PET-CT) in the differential diagnosis of malignant and benign pleural lesions in patients with suspected malignant pleural mesothelioma (MPM). Material and methods: Fifty patients (32 females, 18 males; age range 24-79 years) with pleural thickening, fluid, plaques or calcification on previous CT scan were examined with FDG PET-CT. PET-CT imaging was obtained 1 h after FOG injection. In 12 patients, delayed imaging from the thoracic region was performed 2 h after injection. FDG uptake was evaluated visually and semiquantitively using standardized uptake value (Soy). FOG PET-CT findings were compared with histopathologic diagnosis. Results: Thirty-nine patients had increased FOG uptake in pleural lesions but PET-CT results were negative in 11 patients. When compared with histopathological results in FDG positive group, 34 patients had MPM, 5 had benign pathology: in FDG negative group 8 patients had benign pathology, 3 had MPM. Of patients with delayed imaging, 9 showed increased SUV but 3 had a decreased SUV on delayed images. Increased SUV group had 4 MPM, 5 benign pathology (3 chronic granulomatous inflammation, 2 benign asbestotic plaque). Decreased SUV group all had benign pathology (fibrosis, chronic inflammation, myofibrosis). Discussion: FOG PET-CT is a useful imaging modality in differential diagnosis of malignant and benign pleural lesions. Delayed imaging seems to be useful if there is a decrease in SUV suggesting a benign pathology but does not seem to contribute to the differential diagnosis if the SUV is increased. (C) 2011 Elsevier Espana, S.L. and SEMNIM. All rights reserved.
引用
收藏
页码:187 / 191
页数:5
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